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Pharmaceutical formulation containing gelling agent

  • US 9,517,207 B2
  • Filed: 09/11/2015
  • Issued: 12/13/2016
  • Est. Priority Date: 08/06/2001
  • Status: Expired due to Term
First Claim
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1. A controlled release oral solid dosage form comprising:

  • (i) a first population of coated particles comprising an opioid analgesic coated with a controlled release material, and(ii) a second population of coated particles comprising polyethylene oxide coated with an acrylic polymer,the dosage form providing a therapeutic effect for about 12 hours to about 24 hours when orally administered to a human patient, and when dissolved in from about 0.5 ml to about 10 ml of an aqueous liquid, forming a viscous gel,wherein the coated particles of the second population are about 0.5 mm to about 2 mm in diameter and are free from the opioid analgesic.

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