Implantable pulse generator that generates spinal cord stimulation signals for a human body

• US 9,517,347 B2
• Filed: 07/22/2015
• Issued: 12/13/2016
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Cirtec Medical Corp.
• Original Assignee: Globus Medical, Inc.
• Inventors: Biele, Christopher, Angara, Raghavendra, Khalil, Saif
• Primary Examiner(s): Stice, Paula J
• Application Number:
  US14/805,627
• Publication Number:
  US 20160015982A1
• Time in Patent Office: 510 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/025 Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36178 Burst or pulse train parameters
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37229 Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: A61N 1/3752 Details of casing-lead connections
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body includes an electrode driver for each electrode, which adjusts the amplitude of the timing signals and output an output current corresponding to the adjusted signals for transmission to the associated electrode so as to enable independent amplitude control of the stimulation signals for each stimulation pattern channel.

Claims

1. An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body, comprising:

a signal generator for generating the stimulation signals, said signal generator comprising;

an arbitrator;

a high frequency generator;

control registers storing stimulation signal parameters for a plurality of channels with each channel capable of being associated with at least two electrodes among a plurality of electrodes, each channel representing a stimulation signal pattern of the associated electrodes;

a timing generator adapted to generate timing signals representing stimulation signals for the plurality of channels according to the stored signal parameters;

an electrode driver for each electrode, and adapted to adjust an amplitude of the timing signals from the timing generator according to the stored signal parameters and output an output current corresponding to the adjusted signals for transmission to the associated electrode so as to enable independent control of the amplitude of the stimulation signal for each said channel,

wherein a register bus is configured to allow electronic communication between the arbitrator, the high frequency generator, the timing generator, and the electrode driver for each electrode; and

a treatment control module configured to instruct the signal generator to generate the stimulation signals while a microcontroller electrically connected to the signal generator is in standby mode.

2. The IPG of claim 1, wherein the electrode driver for each electrode includes:

a D/A converter that converts an amplitude parameter within the stored signal parameters to an analog input signal; and

a current driver generating an amplified current signal as the stimulation signal based on the analog input signal from the D/A converter.

3. The IPG of claim 1, wherein the electrode driver for each electrode includes first and second current sources connected in series.

4. The IPG of claim 3, wherein:

a node between the first and second current sources defines an output to an associated electrode; and

the stimulation signal includes a biphasic signal having first and second phases;

the electrode driver further includes;

a first switch positioned between the first current source and the node;

a second switch positioned between the second current source and ground.

5. The IPG of claim 4, wherein the first and second switches selectively turn on and off to source the current from the first current source to the node during one of the phases of the biphasic signal and to sink the current from the second current source to ground during the other phase of the biphasic signal.

6. The IPG of claim 4, wherein:

during one phase of the biphasic signal, the first switch turns on while the second switch turns off to source the current from the first current source to the node; and

during the other phase of the biphasic signal, the first switch turns off while the second switch turns on to sink the current from the second current source to ground.

7. The IPG of claim 1, wherein the signal parameters include an identification of all electrodes that belong to each channel and in which each electrode can be associated with two or more channels.

8. The IPG of claim 1,

wherein the treatment control module is stored in a memory device of the microcontroller and executable by the microcontroller, the treatment control module adapted to transmit the stimulation signal parameters to the control registers and to place the microcontroller in a standby mode, wherein the timing generator is adapted to generate the timing signals according to the stored signal parameters independently from the microcontroller while the microcontroller is in the standby mode.

9. The IPG of claim 1, wherein the arbitrator continuously receives the generated timing signals and selects one channel among the plurality of channels as an active treatment channel.

10. The IPG of claim 1, wherein the high frequency generator is adapted to determine whether to modulate the timing signals received from the timing generator and modulate the received timing signals at a burst frequency according to burst parameters stored in the registers.