Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates

• US 9,518,019 B2
• Filed: 02/10/2016
• Issued: 12/13/2016
• Est. Priority Date: 12/13/2012
• Status: Active Grant

• Current Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Original Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Inventors: Giampietro, Natalie C., Renga, James M.
• Primary Examiner(s): Davis, Zinna Northington
• Application Number:
  US15/040,577
• Publication Number:
  US 20160159742A1
• Time in Patent Office: 307 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: C07C 251/12 being acyclic
• CPC Class Codes: C07D 213/79 Acids; Esters
• CPC Class Codes: C07D 213/803 Processes of preparation

Abstract

4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a C₁-C₄ alkyl propiolate and a substituted methylene amine by a series of steps.

Claims

1. A compound of Formula E

2. A compound of Formula G