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Reservoir device for intraocular drug delivery

  • US 9,522,082 B2
  • Filed: 03/03/2016
  • Issued: 12/20/2016
  • Est. Priority Date: 06/12/2001
  • Status: Expired due to Term
First Claim
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1. A sustained release delivery device, the delivery device comprising:

  • a refillable reservoir having a wall configured to adopt a collapsed configuration having a first cross-sectional dimension and an expanded configuration having a second, larger cross-sectional dimension after insertion into the eye forming a reservoir volume;

    an inlet port in fluid communication with, and near a proximal end of, the reservoir, the inlet port configured for injection of an agent into the reservoir;

    a hollow tube around which the reservoir adopts the collapsed configuration that provides sufficient rigidity for insertion of the reservoir through the scleral wall into the vitreal cavity of an eye, wherein the hollow tube comprises a proximal end and a distal end each extending external to the reservoir volume; and

    a delivery mechanism for controlled, sustained diffusion of the agent to the vitreal cavity, the delivery mechanism in communication with the reservoir volume such that the agent is released from the reservoir volume through the delivery mechanism to the vitreal cavity at a desired rate.

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