Nasal devices

• US 9,522,243 B2
• Filed: 08/03/2015
• Issued: 12/20/2016
• Est. Priority Date: 07/02/2002
• Status: Active Grant

• Current Assignee: OptiNose, Inc.
• Original Assignee: OptiNose AS (OptiNose, Inc.)
• Inventors: Djupesland, Per Gisle
• Primary Examiner(s): Matter, Kristen
• Application Number:
  US14/816,247
• Publication Number:
  US 20160193435A1
• Time in Patent Office: 505 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 15/0021 Mouthpieces therefor
• CPC Class Codes: A61M 15/0051 the dosages being arranged on a tape, e.g. strips
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 15/0091 mechanically breath-triggered
• CPC Class Codes: A61M 15/0098 Activated by exhalation
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2202/04 Liquids
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2202/30 Vaccines
• CPC Class Codes: A61M 2209/06 Packaging for specific medical equipment
• CPC Class Codes: A61M 2209/088 on the body

Abstract

A nasal delivery device and a method of delivering substance to a nasal airway of a subject can be used for mass treatment, especially mass vaccination. The delivery device can include an interface unit, as a replaceable unit, having at least one nosepiece unit for fitting to a respective nostril of a subject, a nozzle from which substance is in use delivered, and at least one delivery unit having a substance supply unit for delivering substance to the nozzle of the at least one nosepiece unit. The delivery device can also include an actuation unit for actuating the at least one delivery unit of the interface unit.

Claims

1. A nasal delivery device for delivering a substance to a nasal airway of a subject, comprising:

an interface unit configured to be attachable to an actuation unit, wherein the interface unit is attachable to the actuation unit in a first unaligned position and is movable to a second aligned position, wherein the interface unit is actuatable only in the aligned position;

the interface unit including a nosepiece unit, a mouthpiece and a delivery unit, the nosepiece unit configured for fitting to a respective nostril of the subject and the delivery unit including a substance supply unit actuatable to deliver the substance to the nosepiece unit.

2. The delivery device of claim 1, wherein the substance is a powder.

3. The delivery device of claim 1, wherein the substance is a liquid.

4. The delivery device of claim 1, wherein the interface unit is a single integral unit.

5. The delivery device of claim 1, wherein the delivery unit is actuated in response to exhalation by the subject.

6. The delivery device of claim 5, wherein the mouthpiece and the nosepiece unit of the interface unit are fluidly connected.

7. The delivery device of claim 1, wherein the interface unit is one of a plurality of interface units each attached to a common support.

8. The delivery device of claim 7, wherein the common support is a belt.

9. A nasal delivery device for delivering a substance to a nasal airway of a subject, comprising:

an interface unit configured to be attachable to an actuation unit, wherein the interface unit is attachable to the actuation unit in a first unaligned position and is slidably movable through the unaligned position to a second aligned position, wherein the interface unit is actuatable only in the aligned position;

the interface unit including a nosepiece unit and a delivery unit, the nosepiece unit configured for fitting to a respective nostril of the subject and the delivery unit including a substance supply unit actuatable to deliver the substance to the nosepiece unit.

10. The delivery device of claim 9, wherein the substance is a powder.

11. The delivery device of claim 9, wherein the substance is a liquid.

12. The delivery device of claim 9, wherein the interface unit is a single integral unit.

13. The delivery device of claim 9, wherein the delivery unit is actuated in response to exhalation by the subject.

14. The delivery device of claim 9, wherein the interface unit further comprises a mouthpiece.

15. The delivery device of claim 14, wherein the mouthpiece and the nosepiece unit of the interface unit are fluidly connected.

16. The delivery device of claim 9, wherein the interface unit is one of a plurality of interface units each attached to a common support.

17. The delivery device of claim 16, wherein the common support is a belt.