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Long-acting oxyntomodulin variants and methods of producing same

  • US 9,522,945 B2
  • Filed: 04/17/2013
  • Issued: 12/20/2016
  • Est. Priority Date: 04/19/2012
  • Status: Active Grant
First Claim
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1. A CTP-modified polypeptide comprising a dual GLP-1/glucagon receptor agonist and one to five chorionic gonadotropin carboxy terminal peptides (CTP) attached to the amino terminus or carboxy terminus of said agonist, wherein said CTP is from the beta-subunit of human chorionic gonadotropin and comprises amino acid positions 1-10 of SEQ ID NO:

  • 3.

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