Analyte monitoring devices and methods

• US 9,526,453 B2
• Filed: 05/16/2016
• Issued: 12/27/2016
• Est. Priority Date: 02/26/2009
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Bernstein, Daniel M.
• Primary Examiner(s): JANG, CHRISTIAN YONGKYUN
• Application Number:
  US15/155,680
• Publication Number:
  US 20160331323A1
• Time in Patent Office: 225 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0214 of power generation or supply
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/1477 non-invasive
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/6833 Adhesive patches

Abstract

On-body units are provided and include a transcutaneous analyte sensor, electronic circuitry electrically coupled to the sensor, and an on-body housing having electrical contacts disposed thereon. The on-body housing comprises a substantially flat surface and a curved and convex surface opposite the substantially flat surface. Systems and methods including the on-body units are also provided. Methods for performing continuity measurements using on-body units are also provided. The methods include positioning an on-body unit (OBU) on a skin of a subject, contacting a continuity test instrument to the OBU; and performing a continuity measurement with the continuity test instrument. An AC signal may be provided across two electrical contacts, or a DC signal may be provided across two electrical contacts in opposite directions for the same amount of time. The measurement may be performed with one electrical contact, or with isolated electrical contacts.

Claims

1. An analyte monitoring system, comprising:

an on-body unit (OBU) for analyte monitoring, the OBU comprising;

a transcutaneous analyte sensor;

electronic circuitry coupled to the analyte sensor; and

an on-body housing comprising a substantially flat surface and a convex surface opposite the substantially flat surface, wherein the on-body housing has electrical contacts disposed on the convex surface, the electrical contacts electrically coupled to the electronic circuitry; and

a hand-held reader comprising a plurality of grooves comprising electrical contacts that electrically couple to the electrical contacts on the on-body housing when the reader is positioned in physical contact with the on-body housing.

2. The analyte monitoring system of claim 1, wherein the on-body housing is dome-shaped.

3. The analyte monitoring system of claim 1, wherein the electronic circuitry comprises first and second RC pairs in series, and wherein the electrical contacts comprise:

a first concentric electrical contact electrically connected between the first and second RC pairs;

a second concentric electrical contact electrically connected to a first end of the first and second RC pairs in series; and

a third concentric electrical contact electrically connected to a second end of the first and second RC pairs in series;

wherein the analyte sensor comprises a working electrode and counter electrode, the working electrode coupled to the second concentric electrical contact, and the counter electrode coupled to the third concentric electrical contact.

4. The analyte monitoring system of claim 3, wherein the OBU comprises isolated contacts for performing continuity measurements, wherein the isolated contacts are disposed on the on-body housing and isolated from the first and second RC pairs.

5. The analyte monitoring system of claim 4, wherein the first, second, and third concentric electrical contacts are ring-shaped, and wherein the isolated contacts are disposed within all three concentric electrical contacts.

6. The analyte monitoring system of claim 5, wherein each isolated contact is ring-shaped and concentrically disposed.

7. The analyte monitoring system of claim 1, wherein the on-body housing is cone-shaped.

8. The analyte monitoring system of claim 1, wherein the electrical contacts comprise first, second, and third concentric electrical contacts disposed on an external surface of the on-body housing.

9. The analyte monitoring system of claim 1, wherein the on-body housing comprises a base perimeter with flat edges or a recessed base perimeter.

10. The analyte monitoring system of claim 1, wherein the electronic circuitry is at least partially powered by the analyte sensor.

11. The analyte monitoring system of claim 1, wherein the analyte sensor is a glucose sensor or a ketone sensor.

12. A method, comprising:

positioning an on-body unit (OBU) on a skin surface, the OBU comprising;

a transcutaneous analyte sensor;

electronic circuitry coupled to the analyte sensor; and

an on-body housing comprising a substantially flat surface and a convex surface opposite the substantially flat surface, wherein the on-body housing has electrical contacts disposed on the convex surface, the electrical contacts electrically coupled to the electronic circuitry;

physically contacting a hand-held reader to the OBU, wherein the hand-held reader comprises a plurality of grooves comprising electrical contacts that electrically couple to the electrical contacts on the on-body housing when the reader physically contacts the on-body housing; and

transmitting an analyte sensor signal from the OBU to the reader via the electrical contacts on the on-body housing and the plurality of electrical contacts on the reader, wherein the analyte sensor signal corresponds to an analyte concentration level.

13. The method of claim 12, wherein the on-body housing is dome-shaped.

14. The method of claim 12, wherein the electronic circuitry comprises first and second RC pairs in series, and wherein the electrical contacts comprise:

a first concentric electrical contact electrically connected between the first and second RC pairs;

a second concentric electrical contact electrically connected to a first end of the first and second RC pairs in series; and

a third concentric electrical contact electrically connected to a second end of the first and second RC pairs in series;

wherein the analyte sensor comprises a working electrode and counter electrode, the working electrode coupled to the second concentric electrical contact, and the counter electrode coupled to the third concentric electrical contact.

15. The method of claim 14, wherein the OBU comprises isolated contacts for performing continuity measurements, wherein the isolated contacts are disposed on the on-body housing and isolated from the first and second RC pairs.

16. The method of claim 15, wherein the first, second, and third concentric electrical contacts are ring-shaped, and wherein the isolated contacts are disposed within all three concentric electrical contacts.

17. The method of claim 16, wherein each isolated contact is ring-shaped and concentrically disposed.

18. The method of claim 12, wherein the on-body housing is cone-shaped.

19. The method of claim 12, wherein the electrical contacts comprise first, second, and third concentric electrical contacts disposed on an external surface of the on-body housing.

20. The method of claim 12, wherein the on-body housing comprises a base perimeter with flat edges or a recessed base perimeter.

21. The method of claim 12, wherein the electronic circuitry is at least partially powered by the analyte sensor.

22. The method of claim 12, wherein the analyte sensor is a glucose sensor or a ketone sensor.