Flow based pressure isolation and fluid delivery system including flow based pressure isolation and flow initiating mechanism

• US 9,526,829 B2
• Filed: 12/22/2014
• Issued: 12/27/2016
• Est. Priority Date: 10/18/2001
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Spohn, Michael A., Haury, John A.
• Primary Examiner(s): MCCALISTER, WILLIAM M
• Application Number:
  US14/579,139
• Publication Number:
  US 20150105674A1
• Time in Patent Office: 736 Days
• Field of Search: 137/516.25, 137/516.27, 137/519, 137/485, 137/877, 137/519.5, 600/485, 600/486, 600/487, 600/488, 604/140
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02141 Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits A61B5/02233, A61B5/0235 take precedence
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61M 2005/1403 Flushing or purging
• CPC Class Codes: A61M 2039/229 Stopcocks
• CPC Class Codes: A61M 2039/2433 Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
• CPC Class Codes: A61M 2039/2453 not being fixed to the valve body
• CPC Class Codes: A61M 2039/2473 Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
• CPC Class Codes: A61M 2039/248 Ball-valve
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3362 with minimised length of fluid lines; Taking into account the elastic expansion of fluid lines to increase accuracy
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/16881 : Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: A61M 5/172 : electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/365 : Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626
• CPC Class Codes: Y10T 137/0352 : Controlled by pressure
• CPC Class Codes: Y10T 137/7758 : Pilot or servo controlled
• CPC Class Codes: Y10T 137/7871 : Weight biased
• CPC Class Codes: Y10T 137/7915 : Guide stem
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/87829 : Biased valve

Abstract

The fluid delivery system includes a pressurizing device for delivering a pressurized injection fluid, a low pressure fluid delivery system, and a pressure isolation mechanism adapted for fluid communication with the pressurizing device and low pressure fluid delivery system. The pressure isolation mechanism includes a housing defining an inlet port, an isolation port, and an internal cavity. The housing defines a seal seat in the internal cavity between the inlet port and isolation port. A valve member is disposed in the internal cavity. The valve member is free floating in the internal cavity and is adapted to engage the seal seat. The valve member has an open position permitting fluid communication between the inlet port and isolation port, and is fluid flow responsive to fluid flow in the inlet port to engage the seal seat and attain a closed position preventing fluid flow between the inlet port and isolation port.

Claims

1. A method of protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism comprising an inlet port, an isolation port, an internal cavity wherein a free floating, fluid flow responsive valve member is disposed and adapted to engage a seal seat in the internal cavity, a flow initiating mechanism associated with the isolation port, and a retainer retaining the flow initiating mechanism in fluid communication with the isolation port, the method comprising:

associating the pressure transducer with the isolation port;

placing a pressurizing device for delivering a fluid under pressure in fluid connection with the inlet port;

actuating the pressurizing device to cause fluid flow in the inlet port such that the free floating, fluid flow responsive valve member engages the seal seat to attain a substantially closed position and prevent fluid flow between the inlet port and the isolation port;

wherein upon actuation of the pressure device, the flow initiating mechanism initiates flow around the valve member such that the valve member operates to the substantially closed position upon fluid flow initiation; and

wherein the retainer prevents pressure relief venting of the fluid to atmosphere.

2. The method of claim 1, further comprising deactuating the pressurizing device and allowing the valve member to attain an open position disengaged from the seal seat permitting fluid communication between the inlet port and isolation port.

3. The method of claim 2, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted via the fluid communication between the inlet port and the isolation port in the open position of the valve member.

4. The method of claim 1, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted at least in part through a body of the valve member or a portion thereof in the substantially closed position.

5. The method of claim 4, wherein the body of the valve member or a portion thereof comprises a compliant material.

6. The method of claim 5, wherein the compliant material is selected to transmit hemodynamic pressure signals through the valve member to the pressure transducer associated with the isolation port.

7. The method of claim 2, wherein the valve member attains the open position by reverse fluid flow generated in the isolation port.

8. The method of claim 1, wherein the inlet port is placed in fluid communication with the pressurizing device by using a fitting to connect the inlet port to the pressurizing device.

9. The method of claim 8, wherein the fitting comprises a Y-T fitting.

10. A method of protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism comprising an inlet port, an isolation port, an internal cavity wherein a free floating, fluid flow responsive valve member is disposed and adapted to engage a seal seat in the internal cavity, a flow initiating mechanism comprising a flow initiating member associated with the isolation port, and a retainer retaining the flow initiating mechanism in fluid communication with the isolation port, the method comprising:

associating the pressure transducer with the isolation port;

placing a pressurizing device for delivering a fluid under pressure in fluid connection with the inlet port;

actuating the pressure device to cause fluid flow in the inlet port such that the free floating, fluid flow responsive valve member engages the seal seat to attain a substantially closed position and prevent fluid flow between the inlet port and the isolation port;

wherein the flow initiating member provides upstream capacitance to initiate fluid flow around the valve member such that the valve member operates to the substantially closed position upon fluid flow initiation and operates to an open position upon fluid flow cessation; and

wherein the retainer prevents pressure relief venting of the fluid to atmosphere.

11. The method of claim 10, further comprising deactuating the pressurizing device and allowing the upstream capacitance to act upon the valve member to attain the open position disengaged from the seal seat permitting fluid communication between the inlet port and isolation port.

12. The method of claim 11, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted via the fluid communication between the inlet port and the isolation port in the open position of the valve member.

13. The method of claim 10, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted at least in part through a body of the valve member or a portion thereof in the substantially closed position.

14. The method of claim 13, wherein the body of the valve member or a portion thereof comprises a compliant material.

15. The method of claim 14, wherein the compliant material is selected to transmit hemodynamic pressure signals through the valve member to the pressure transducer associated with the isolation port.

16. The method of claim 10, wherein the valve member attains the open position by reverse fluid flow generated in the isolation port caused by the upstream capacitance.

17. The method of claim 10, wherein the inlet port is placed in fluid communication with the pressurizing device by using a fitting to connect the inlet port to the pressurizing device.

18. The method of claim 17, wherein the fitting comprises a Y-T fitting.

19. The method of claim 10, the pressure isolation mechanism further comprising an air inlet prevention filter disposed in the retainer and adapted to prevent air from entering the internal cavity when the filter is wetted, the method further comprising:

wetting the air inlet prevention filter with the fluid.

20. The method of claim 10, wherein the actuating of the pressure device causes the flow initiating member to compress axially to store the upstream capacitance.