Composition and method to form a self decontaminating surface

• US 9,528,009 B2
• Filed: 12/07/2012
• Issued: 12/27/2016
• Est. Priority Date: 04/15/2011
• Status: Active Grant

• Current Assignee: SRFC Bio Incorporated
• Original Assignee: Allied Bioscience, Inc.
• Inventors: Grossman, Craig, Ngo, Mai, Wysocki, Ronald
• Primary Examiner(s): Shah, Samir
• Application Number:
  US13/708,613
• Publication Number:
  US 20140158018A1
• Time in Patent Office: 1,481 Days
• US Class Current: 1/1
• CPC Class Codes: A01N 37/36 containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: C09D 5/14 Paints containing biocides, e.g. fungicides, insecticides or pesticides C09D5/16 takes precedence
• CPC Class Codes: C09D 5/1618 inorganic

Abstract

A method to prepare a self-decontaminating surface, where that method includes dissolving tartaric acid in water, adding titanium (IV) isopropoxide to the tartaric acid solution to form a coating composition in water, and casting that coating composition onto a surface to form a coating having anti-microbial function.

Claims

1. A coating disposed on a surface, formed by the method consisting of:

dissolving tartaric acid in water;

forming an opaque gel by adding titanium (IV) isopropoxide to said tartaric acid solution to form an 18 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

diluting said gel with water to form a 10 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

casting said 10 weight percent aqueous gel onto a surface to form a coating;

inoculating said surface with MRSA bacteria,

wherein;

said inoculated surface comprises an initial MRSA concentration;

said inoculated surface shows greater than a log 5.6 reduction in MRSA concentration after 2 hours.

2. A coating disposed on a surface, formed by:

dissolving tartaric acid in water;

forming an opaque gel by adding titanium (IV) isopropoxide to said tartaric acid solution to form an 18 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

diluting said gel with water to form a 3 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

casting said 3 weight percent aqueous gel onto a surface to form a coating;

inoculating said surface with MRSA bacteria,

wherein;

said inoculated surface comprises an initial MRSA concentration; and

said inoculated surface shows a greater than log 5.5 reduction in MRSA concentration after 2 hours.

3. A coating disposed on a surface, formed by:

dissolving tartaric acid in water;

forming an opaque gel by adding titanium (IV) isopropoxide to said tartaric acid solution to form an 18 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

diluting said gel with water to form a 1 weight percent loading of tartaric acid and titanium (IV) isopropoxide in water;

casting said 1 weight percent aqueous gel onto a surface to form a coating;

inoculating said surface with MRSA bacteria,

wherein;

said inoculated surface comprises an initial MRSA concentration; and

said inoculated surface shows a log 1.8 reduction in MRSA concentration after 2 hours.