System and method for adjusting the light output of an optoacoustic imaging system

• US 9,528,936 B2
• Filed: 03/31/2014
• Issued: 12/27/2016
• Est. Priority Date: 12/31/2011
• Status: Active Grant

• Current Assignee: Seno Medical Instruments, Inc.
• Original Assignee: Seno Medical Instruments, Inc.
• Inventors: Schmid, Gregory
• Primary Examiner(s): LE, QUE TAN
• Application Number:
  US14/230,477
• Publication Number:
  US 20140208856A1
• Time in Patent Office: 1,002 Days
• Field of Search: 250/205, 250/208.1, 250/214.R, 250/370.09, 250/459.1, 250/458.1, 250/363.01, 600160-182, 600476-478
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0035 adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 8/0825 for diagnosis of the breast, e.g. mammography
• CPC Class Codes: A61B 8/14 Echo-tomography
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/4444 related to the probe
• CPC Class Codes: A61B 8/54 Control of the diagnostic device
• CPC Class Codes: A61B 8/587 Calibration phantoms models for medical purposes G09B23/28
• CPC Class Codes: G01N 21/1702 with opto-acoustic detection, e.g. for gases or analysing solids
• CPC Class Codes: G01N 21/63 optically excited
• CPC Class Codes: G01N 2201/0221 Portable; cableless; compact; hand-held
• CPC Class Codes: G01N 29/04 Analysing solids using acoustic emission techniques G01N29/14
• CPC Class Codes: G01N 29/045 by imparting shocks to the workpiece and detecting the vibrations or the acoustic waves caused by the shocks measuring resonant frequency G01H13/00; measuring strength properties by application of mechanical stress G01N3/00

Abstract

A system and method for adjusting the light output of an optoacoustic imaging system is presented. An optoacoustic imaging system includes a light source such as a laser, the light source having a light output control, a probe for delivering light to a volume, the probe being associated with one or more sensors, a light path operatively connected to the first light source, the light path providing light from the first light source to the probe. Generally, the light output of an optoacoustic imaging system may be harmful to the eye, and may be subject to maximum safe fluence levels incident upon the volume of interest in a clinical setting. Accordingly, the light output control may be set to an initial, relatively low value. After the light source is pulsed, the light output may be measured at or near the probe at the distal end of the light path. The measured light output can used to determine whether, and how much, to change the setting of the light output control. The system and method may also be used for closed loop control of the light output to keep fluence levels within a desired range. The rate of change of the light output control can be varied based upon the difference between the measured fluence and the desired fluence or range.

Claims

1. A method for adjusting the light output of an optoacoustic imaging system from an initial level to an operating level, the optoacoustic imaging system comprising a first light source having a light output control, a probe for delivering light to a volume, the probe being associated with one or more sensors, a light path operatively connected to the first light

source, the light path providing light from the first light source to the probe, the method comprising the steps of:

a. setting the light output control of the first light source to an initial value;

b. pulsing the first light source, thereby delivering light to the probe and the volume;

c. taking a measurement from the one or more sensors;

d. changing the setting of the light output control of the first light source based upon the measurement from the one or more sensors; and

e. repeating steps b-d prior to the operating level being reached.

2. The method for adjusting the light output claimed in claim 1, wherein the operating level is a predetermined level of fluence incident upon the volume.

3. The method for adjusting the light output level claimed in claim 2, wherein the step of changing the setting of the light output control comprises the steps of:

inferring a light fluence incident upon the volume based upon the measurement from the one or more sensors;

determining a difference between the inferred fluence incident upon the volume and the predetermined level of fluence incident upon the volume;

determining a change value based upon the determined difference; and

changing the setting of the light output control of the first light source by an amount equal to the change value.