Reperfusion injury devices

• US 9,533,124 B2
• Filed: 04/14/2011
• Issued: 01/03/2017
• Est. Priority Date: 04/14/2011
• Status: Expired due to Fees

• Current Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories Incorporated)
• Inventors: Mack, Matthew M., Spaeder, Jeffrey Allen, Ehrenreich, Kevin Joe, Toner, John L., Consigny, Paul Macke, Hossainy, Syed Faiyaz Ahmed, Basu, Shubhayu
• Primary Examiner(s): YABUT, DIANE D
• Application Number:
  US13/086,664
• Publication Number:
  US 20120265283A1
• Time in Patent Office: 2,091 Days
• Field of Search: 623/1.11
• US Class Current: 1/1
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61M 2025/0004 having two or more concentrically arranged tubes for forming a concentric catheter system
• CPC Class Codes: A61M 2025/0006 which can be secured against axial movement, e.g. by using a locking cuff
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 2025/1015 having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61M 25/10182 Injector syringes
• CPC Class Codes: A61M 25/10185 Valves
• CPC Class Codes: A61M 25/10188 Inflation or deflation data displays
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

A catheter configured for performing reperfusion by alternatively occluding a vessel so as to prevent fluid flow and removing that occlusion to allow fluid flow is described. A first catheter includes an outer member and a retractable valve to allow and prevent fluid flow in the vessel. A second catheter includes a sheathed expansion member that can be deployed and recaptured to prevent and allow, respectively, fluid flow. A third catheter includes an angioplasty balloon to open a vessel occlusion, in which an occlusion balloon is used to allow and disallow fluid flow. A fourth catheter includes an expandable member for providing mechanical plunging action to urge thrombotic material to a more distal location. A fifth catheter includes an accessory catheter that can be used to perform reperfusion with another catheter. A sixth catheter includes an inner balloon within an outer balloon configured to perform reperfusion.

Claims

1. A reperfusion catheter, comprising:

an inner member having a proximal shaft portion, a distal shaft portion, and a guidewire lumen, wherein the distal shaft portion includes an inlet hole, a distal port, and a fluid lumen coupling the inlet hole and the distal port, and wherein the inlet hole is in fluid communication with the distal port;

an expandable stent on the distal shaft portion of the inner member and located between the inlet hole and the distal port, wherein the expandable stent includes a side wall;

a cover over the side wall of the expandable stent, wherein the cover includes a proximal end sealed around the inner member distal to the inlet hole; and

an outer member that is moveable relative to the inner member, the cover, and the expandable stent between a first position wherein the outer member extends at least partially over the cover and the expandable stent, and a retracted position wherein a distal end of the outer member is disposed proximal to the cover and the expandable stent, the outer member having an inner lumen capable of sliding over the inner member and the cover to capture the expandable stent;

wherein, when the outer member is in the first position within a blood vessel, the distal end of the outer member contacts the cover to block blood flow into the inlet hole, and wherein, when the outer member is in the retracted position within the blood vessel, the inlet hole is disposed between the distal end of the outer member and the cover to allow blood flow into the inlet hole.

2. The reperfusion catheter of claim 1, wherein the guidewire lumen is capable of delivering a therapeutic agent distal to the reperfusion catheter.

3. The reperfusion catheter of claim 1 further comprising a radio-opaque marker on the inner member to locate the expandable stent in a body lumen.

4. The reperfusion catheter of claim 1, wherein the expandable stent includes a self-expanding structure.

5. The reperfusion catheter of claim 4, wherein the cover includes a polymer.

6. The reperfusion catheter of claim 5, wherein the expandable stent includes a tapered shape.

7. The reperfusion catheter of claim 6, wherein the tapered shape includes a gradual transition surface to allow the cover and the expandable stent to be collapsed when the outer member is advanced over the expandable stent.