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Dual-functional nonfouling surfaces comprising target binding partner covalently coupled to polymer attached to substrate

  • US 9,535,062 B2
  • Filed: 08/27/2014
  • Issued: 01/03/2017
  • Est. Priority Date: 12/29/2006
  • Status: Active Grant
First Claim
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1. A block copolymer having a plurality of covalently coupled target binding partners having affinity toward a target molecule, the block copolymer having a first hydrophilic block and a second hydrophobic block, wherein the hydrophilic block comprises a plurality of carboxylic acid groups and a plurality of positive charged groups, wherein the hydrophilic block is substantially electronically neutral, and wherein the target binding partners are selected from the group consisting of enzymes, antibodies, protein-based antigens, receptors, polysaccharide ligands, and oligosaccharides ligands.

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