Medical sensor system for detecting a feature in a body
First Claim
1. A medical sensor system for detecting a feature in a body, the system including:
- a. a signal pick-up unit configured to be implanted within the body, the signal pick-up unit including;
(1) a magnetic nanoparticle having a coating consisting essentially of a receptor, the receptor being configured to competitively bind to;
(a) an analyte, and(b) an analog of the analyte,as a function of a concentration of the analyte;
(2) at least one polymer of monomers from;
(a) N-isopropylacrylamide,(b) N,N-diethylacrylamide,(c) methyl vinyl ether,(d) N-vinylcaprolactam,(e) ethylene oxide-co-propylene oxide,(f) lactic acid,(g) glycolic acid,(h) trimethylcarbonate,(i) acrylate,(j) methacrylate,(k) hydroxyethyl-metacrylate,(l) vinyl ester;
b. a signal processing unit;
(1) spatially separated from the signal pick-up unit, and(2) including;
(a) a transmitter configured to emit an alternating magnetic field which acts on the signal pick-up unit to generate a response signal from the signal pick-up unit, and(b) a receiver configured to receive the response signal of the signal pick-up unit.
1 Assignment
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Accused Products
Abstract
The invention relates to a medical sensor system (10a/10c) for detecting a feature (12a/12c) in a human or animal body (14a/14c), including a signal pick-up unit (16a/16c), which can be implanted in the animal and/or human body (14a/14c), and a signal processing unit (18a/18c), which is spatially separated from the signal pick-up unit (16a/16c) and which includes a transmitter (20a/20c) and a receiver (22a/22c). The transmitter (20a/20c) emits an alternating magnetic field (24a/24c) to act on the signal pick-up unit (16a/16c), and the receiver (22a/22c) receives a response signal (26a/26c) of the signal pick-up unit (16a/16c), which is generated by the magnetic interaction of the alternating magnetic field (24a/24c) with the signal pick-up unit (16a/16c).
7 Citations
25 Claims
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1. A medical sensor system for detecting a feature in a body, the system including:
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a. a signal pick-up unit configured to be implanted within the body, the signal pick-up unit including; (1) a magnetic nanoparticle having a coating consisting essentially of a receptor, the receptor being configured to competitively bind to; (a) an analyte, and (b) an analog of the analyte, as a function of a concentration of the analyte; (2) at least one polymer of monomers from; (a) N-isopropylacrylamide, (b) N,N-diethylacrylamide, (c) methyl vinyl ether, (d) N-vinylcaprolactam, (e) ethylene oxide-co-propylene oxide, (f) lactic acid, (g) glycolic acid, (h) trimethylcarbonate, (i) acrylate, (j) methacrylate, (k) hydroxyethyl-metacrylate, (l) vinyl ester; b. a signal processing unit; (1) spatially separated from the signal pick-up unit, and (2) including; (a) a transmitter configured to emit an alternating magnetic field which acts on the signal pick-up unit to generate a response signal from the signal pick-up unit, and (b) a receiver configured to receive the response signal of the signal pick-up unit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 23)
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12. A method for detecting an analyte in a body using a sensor system, the system including:
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A. a signal pick-up unit configured to be implanted within the body, the signal pick-up unit including; I. a magnetic nanoparticle, II. a hydrogel, the hydrogel including an analog of the analyte, and III. a coating on the nanoparticle, the coating consisting essentially of a receptor of the analyte and analog, B. a signal processing unit spatially separated from the signal pick-up unit, the signal processing unit including a transmitter and a receiver; wherein the method includes the steps of; a. transmitting an alternating magnetic field from the transmitter, the magnetic field acting on the signal pick-up unit to generate a response signal therefrom; b. receiving the response signal of the signal pick-up unit at the receiver. - View Dependent Claims (13, 14, 15, 18, 24)
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16. A medical sensor system for detecting an analyte in a body, the system including:
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a. a signal pick-up unit configured to be implanted within the body, the signal pick-up unit including (1) a hydrogel, and (2) a magnetic nanoparticle being configured to exhibit a magnetic property dependent on the concentration of the analyte within the body, (3) a coating on the magnetic nanoparticle, the coating consisting essentially of a receptor of; (a) an analyte, and (b) an analog of the analyte, whereby the magnetic nanoparticle may reversibly bind to the analyte and analog via the receptor; b. a signal processing unit; (1) situated outside the body, and (2) including; (a) a transmitter configured to emit an alternating magnetic field, and (b) a receiver configured to receive a response signal from at least the magnetic nanoparticle of the signal pick-up unit, the response signal being induced by the alternating magnetic field. - View Dependent Claims (17, 19, 20, 21, 22, 25)
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Specification