Vaso-occlusive device delivery system

• US 9,539,011 B2
• Filed: 03/12/2014
• Issued: 01/10/2017
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker European Holdings I, LLC (Stryker Corporation)
• Inventors: Chen, Hancun, Teoh, Clifford, Guo, Lantao, Odell, Timothy, Murphy, Richard
• Primary Examiner(s): Eastwood, David C
• Application Number:
  US14/206,371
• Publication Number:
  US 20140277094A1
• Time in Patent Office: 1,035 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/12068 detachable by heat

Abstract

A vaso-occlusive device delivery assembly includes a pusher assembly having a proximal end, a distal end, and a pusher lumen extending therebetween; a vaso-occlusive device; and a tubular member mechanically connecting the pusher assembly to the vaso-occlusive device, the tubular member having a proximal end, a distal end, a tube lumen extending therebetween, and a detach zone, wherein the proximal end of the tubular member extends into the pusher assembly lumen at the distal end of the pusher assembly. A heat generating member is disposed in the tube lumen, such that, when activated, the heat generating member generates heat that melts or otherwise thermally degrades the tubular member at the detach zone, thereby detaching the vaso-occlusive device from the pusher assembly.

Claims

1. A vaso-occlusive device delivery assembly, comprising:

a pusher assembly having a proximal end, a distal end, and a pusher lumen extending therebetween;

a vaso-occlusive device; and

a tubular member mechanically connecting the pusher assembly to the vaso-occlusive device, the tubular member having a proximal end, a distal end, a tube lumen extending therebetween, and a detach zone,

proximal and distal seals attached to, and forming respective seal with, the respective proximal and distal ends of the tubular member, such that the tubular member, proximal seal, and distal seal, collectively form a substantially fluid-tight chamber within the tube lumen,

wherein the proximal end of the tubular member extends into the pusher assembly lumen at the distal end of the pusher assembly, and

wherein a heat generating member is disposed in the tube lumen, such that, when activated, the heat generating member generates heat that melts or otherwise thermally degrades the tubular member at the detach zone, thereby detaching the vaso-occlusive device from the pusher assembly.

2. The vaso-occlusive device delivery assembly of claim 1, the pusher assembly further comprising first and second conductors extending between the proximal and distal ends of the pusher assembly,

wherein the heat generating member is a resistive heater coil electrically connected to the respective first and second conductors to form an electrical circuit, and

wherein the heat generating member is activated by applying a current therethrough.

3. The vaso-occlusive device delivery assembly of claim 2, wherein a pitch of a proximal portion of the heater coil is greater than a pitch of a distal portion of the heater coil, such that the heater coil has a non-uniform heat distribution.

4. The vaso-occlusive device delivery assembly of claim 1, wherein the detach zone is treated to accelerate detachment of the vaso-occlusive device from the pusher assembly.

5. The vaso-occlusive device delivery assembly of claim 4, wherein the detach zone is thermally weakened.

6. The vaso-occlusive device delivery assembly of claim 4, wherein the detach zone is mechanically weakened.

7. The vaso-occlusive device delivery assembly of claim 1, further comprising an elongate body disposed in the tube lumen at the distal end of the tubular member, wherein a distal portion of the tubular member is attached to an outer surface of the elongate body, thereby increasing a tension on the detach zone to accelerate detachment of the vaso-occlusive device from the pusher assembly.

8. The vaso-occlusive device delivery assembly of claim 1, further comprising a locking coil disposed in the tube lumen at the distal end of the tubular member, wherein both the locking coil and the distal end of the tubular member are disposed in a lumen of the vaso-occlusive device, the locking coil sized so as to increase an interference fit between the tubular member and the vaso-occlusive device.

9. The vaso-occlusive device delivery assembly of claim 1, wherein the pusher assembly further comprises a cylindrical body disposed around and thermally insulating the detach zone, and wherein the cylindrical body is configured to increase an axial columnar strength of the vaso-occlusive device delivery assembly.

10. The vaso-occlusive device delivery assembly of claim 1, wherein the tubular member comprises a radially enlarged distal portion, and wherein a proximal end of the vaso-occlusive device is secured to the tubular member by an interference fit within the radially enlarged distal portion of the tubular member.

11. The vaso-occlusive device delivery assembly of claim 1, wherein the proximal end of the tubular member is connected to the pusher assembly by a first adhesive connection and the distal end of the tubular member is connected to the vaso-occlusive device by a second adhesive connection.

12. The vaso-occlusive device delivery assembly of claim 2, wherein the first and second conductors extend through the proximal seal, and wherein the proximal seal maintains a substantially fluid-tight seal in the tube lumen.

13. The vaso-occlusive device delivery assembly of claim 1, the vaso-occlusive device comprising a stretch-resisting member having a distal end secured to a distal portion of the vaso-occlusive device, and a proximal end secured to an adapter disposed in a proximal end portion of a lumen of the vaso-occlusive device.

14. The vaso-occlusive device delivery assembly of claim 13, wherein the adapter comprises a flattened body defining an opening in the distal end thereof, and wherein the stretch-resisting member forms a loop passing through the opening, thereby attaching the stretch-resisting member to the adapter.

15. The vaso-occlusive device delivery assembly of claim 13, wherein the adapter comprises a coil, and wherein the stretch-resisting member forms a loop passing through an open winding in the distal end of the coil, thereby attaching the stretch-resisting member to the adapter.

16. The vaso-occlusive device delivery assembly of claim 1, wherein the heat generating member is configured to heat air within the pusher lumen to thereby increase a pressure therein to accelerate detachment of the vaso-occlusive device from the pusher assembly.

17. The vaso-occlusive device delivery assembly of claim 1, wherein the heat generating member comprises carbon.

18. The vaso-occlusive device delivery assembly of claim 1, wherein the tubular member comprises a polymer selected from the group consisting of high-density polyethylene, low-density polyethylene, polypropylene, polyethylene terephthalate, and polycaprolactone.

19. The vaso-occlusive device delivery assembly of claim 1, wherein the tubular member comprises a plurality of concentric layers, and wherein the tubular member comprises a low melting point inner layer and a high melting point outer layer.