Aneurysm treatment device and method of use

• US 9,539,122 B2
• Filed: 03/24/2014
• Issued: 01/10/2017
• Est. Priority Date: 07/20/2001
• Status: Expired due to Term

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Microvention Incorporated (Terumo Corporation)
• Inventors: Burke, Thomas H., Cox, Brian J., Fitz, Matthew J., Ferrera, David
• Primary Examiner(s): SZPIRA, JULIE ANN
• Application Number:
  US14/223,939
• Publication Number:
  US 20140288633A1
• Time in Patent Office: 1,023 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body

Abstract

An apparatus for treating vascular aneurysms includes an occlusive support device comprised of one or more support members. The occlusive device has, an end cap member and an anchoring member. The end cap member is comprised of at least one of one or more of the support members. The end cap member has openings and the end cap member comprises a reactive material that is configured to hydrate upon delivery of the device and to reduce the size of said openings. The device is configured so that the occlusive members can be positioned in the blood vessel proximate the neck of a vascular aneurysm, the reactive material hydrates and increases the resistance to blood flow into the aneurysm, and the anchoring member anchors the device in the blood vessel without occluding flow through the blood vessel.

Claims

1. An apparatus for treating vascular aneurysms, comprising:

an occlusive support device comprising one or more support members forming a first end portion and a second end portion and defining a lumen therethrough; and

a rounded end cover member forming a longitudinal sidewall at said first end portion of said occlusive support device;

wherein said end cover member has openings and said end cover member comprises a reactive material that is configured to hydrate upon delivery of the device and to reduce the size of said openings;

an anchoring member at said second end portion; and

,

a plurality of elongated members along said longitudinal axis and connecting said end cover member to said anchoring member, said elongated members having a length selected to span across a blood vessel adjacent to a targeted aneurysm to connect the anchoring member to the end cover while minimizing resistance to blood flow through the adjacent blood vessel.

2. The apparatus of claim 1 wherein said end cover member comprises at least one of said one or more support members.

3. The apparatus of claim 1 wherein said end cover member comprises a support member formed in a circular shape of decreasing diameter.

4. The apparatus of claim 1 wherein said end cover member comprises a plurality of interwoven support members forming a fenestrated end cover.

5. The apparatus of claim 1 wherein said reactive material is applied to said end cover member.

6. The apparatus of claim 1 wherein said end cover member comprises a porous material.

7. The apparatus of claim 1, wherein said end cover is capable of increasing the resistance of blood flow therethrough.

8. The apparatus of claim 1 wherein said end cover member comprises one or more filamentary elements.

9. The apparatus of claim 8 wherein said filamentary elements are arranged to form an end cover member selected from the group consisting of a coil, a weave, a braid, a mesh, a screen, and a cable.

10. The apparatus of claim 1 wherein said reactive material is a hydrogel.

11. The apparatus of claim 1 wherein said reactive material in configured to expand in response to changes in physiological pH.

12. The apparatus of claim 1 wherein said end cover member comprises a mesh member comprised of a plurality of wires.

13. The apparatus of claim 12 wherein said mesh member is comprised of fine, self-expanding wires.

14. The apparatus of claim 12 wherein said mesh member is a low porosity mesh member.

15. The apparatus of claim 14 wherein said low porosity member is a nonporous barrier.

16. The apparatus of claim 1 wherein said end cover has an extension along said longitudinal axis of said device that is less than said end cover diameter.

17. The apparatus of claim 1 wherein said end cover has an extension along said longitudinal axis of said device that is less than two times said end cover diameter.

18. The apparatus of claim 1, wherein said support device is substantially cylindrical and said support device comprises one or more support members along said longitudinal axis and defining fenestrations through said support device.

19. The apparatus of claim 18 wherein said end cover member comprises a plurality of said one or more support members interwoven together.

20. The apparatus of claim 1 wherein said anchoring member is a stent.

21. The apparatus of claim 20 wherein said stent is comprised of support members defining fenestrations through said support device.

22. The apparatus of claim 1 wherein said end cover member is comprised of self-expanding end cover member wires and said elongated members comprise the same self-expanding material as said end cover member and said elongated members comprise wires of the same size as said end cover member wires.

23. The apparatus of claim 22 wherein said elongated members are extensions of said end cover member wires.

24. The apparatus of claim 22 wherein said elongated members are attached to said end cover member.

25. The apparatus of claim 22 wherein said anchoring member is comprised of the same self-expanding material as said end cover member and said elongated members.

26. The apparatus of claim 22 wherein said elongated members are an extension of said anchoring member.

27. An apparatus for treating vascular aneurysms, comprising:

an occlusive support device comprising a longitudinal axis having first end portion and a second end portion;

a rounded end cover member forming a longitudinal sidewall at said first end portion of said occlusive support device, wherein said end cover member has an end cover diameter and said end cover is generally perpendicular to said longitudinal axis of said support device, wherein said end cover has an extension along said longitudinal axis of said device that is less than two times said end cover diameter and wherein said end cover member has openings and said end cover member comprises a reactive material that is configured to hydrate upon delivery of the device and to reduce the size of said openings; and

an anchoring member at said second end portion;

elongated members connecting the first end portion to the second end portion, said elongated members having a length selected to span across a blood vessel adjacent to a targeted aneurysm to connect the anchoring member to the end cover member while minimizing resistance to blood flow through the adjacent blood vessel.

28. The apparatus of claim 27 wherein said reactive material in configured to expand in response to changes in physiological pH.

29. An apparatus for treating vascular aneurysms, comprising:

an occlusive support device comprising one or more support members forming a first end portion and a second end portion and defining a lumen therethrough; and

a rounded mesh end cover member at said first end portion of said occlusive support device, said mesh end cover member comprised of at least one of said one or more support members, said rounded mesh end cover member forming a longitudinal sidewall;

wherein said end cover member has openings and said end cover member comprises a reactive material that is configured to hydrate upon delivery of the device and to reduce the size of said openings; and

an anchoring member at said second end portion;

elongated members connecting the first end portion to the second end portion, said elongated members having a length selected to span across a blood vessel adjacent to a targeted aneurysm to connect the anchoring member to the end cover while minimizing resistance to blood flow through the adjacent blood vessel.

30. The apparatus of claim 29 wherein said reactive material in configured to expand in response to changes in physiological pH.