Porcine lactic acid bacterial strains
First Claim
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1. A composition comprising at least one porcine lactic acid bacterial strain wherein said at least one porcine lactic acid bacterial strain is selected from the group consisting of:
- NCIMB 41846;
NCIMB 41847;
NCIMB 41848;
NCIMB 41849;
NCIMB 41850;
NCIMB 42008;
NCIMB 42009;
NCIMB 42010;
NCIMB 42011;
NCIMB 42012; and
any combination of two or more thereof;
and an excipient, diluent or carrier;
wherein said at least one porcine lactic acid bacterial strain is in an amount sufficient to treat or prevent an intestinal disorder in a subject.
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Abstract
Described herein are porcine lactic acid bacterial strain compositions and processes of obtaining porcine lactic acid bacterial strains. Further aspects of the invention relate to food additives, supplements and probiotic compositions comprising said bacterial strains, and therapeutic uses of said bacterial strain compositions.
62 Citations
14 Claims
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1. A composition comprising at least one porcine lactic acid bacterial strain wherein said at least one porcine lactic acid bacterial strain is selected from the group consisting of:
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NCIMB 41846; NCIMB 41847; NCIMB 41848; NCIMB 41849; NCIMB 41850; NCIMB 42008; NCIMB 42009; NCIMB 42010; NCIMB 42011; NCIMB 42012; and
any combination of two or more thereof;and an excipient, diluent or carrier; wherein said at least one porcine lactic acid bacterial strain is in an amount sufficient to treat or prevent an intestinal disorder in a subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 13, 14)
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11. A method of preparing one or more porcine lactic acid bacterial strains, said method comprising the steps of:
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(i) obtaining faeces from an organically reared pig; (ii) freezing the faeces and dispersing in a suitable diluent; (iii) applying the dispersed faeces obtained in step (ii) to a suitable agar, optionally in the presence of supplemental pig colostrum carbohydrates, and incubating under an anaerobic conditions; (iv) selecting off distinct colonies of bacteria formed during step (iii) and seeding into a suitable broth, optionally in the presence of supplemental pig colostrum carbohydrates; (v) incubating the seeded colonies obtained in step (iv) and (vi) obtaining an aliquot of the incubated broth, said aliquot comprising one or more porcine lactic acid bacterial strains selected from the group consisting of;
NCIMB 41846;
NCIMB 41847;
NCIMB 41848;
NCIMB 41849;
NCIMB 41850;
NCIMB 42008;
NCIMB 42009;
NCIMB 42010;
NCIMB 42011;
NCIMB 42012; and
any combination of two or more thereof.
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12. A lactic acid bacterial strain comprising a 16S rRNA gene sequence selected from SEQ ID NOs 1-87, or a variant or homologue thereof of said sequence.
Specification