Acoustic streaming glaucoma drainage device

• US 9,545,337 B2
• Filed: 09/05/2013
• Issued: 01/17/2017
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Novartis Ag
• Inventors: Yalamanchili, Satish, Ovchinnikov, Mikhail, Zhou, Jianbo
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US14/019,234
• Publication Number:
  US 20140276343A1
• Time in Patent Office: 1,230 Days
• Field of Search: 604/8, 604/9, 604/107, 604/108, 623/4.1, 623/1.12, 424/422, 424/423
• US Class Current: 1/1
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

An acoustic streaming valve arrangement induces flow in a glaucoma drainage device. The arrangement may include a selectively vibrating flow generator having a sharp edge and a driving device configured to selectively vibrate the flow generator to create a streaming fluid flow in a direction away from the sharp edge.

Claims

1. An acoustic streaming valve arrangement for inducing flow in a glaucoma drainage device, comprising:

a valve portion configured to selectively inhibit fluid flow between a fluid inlet and a fluid outlet, wherein the valve portion comprises;

a boss portion including a seat; and

a flexible portion, wherein the flexible portion selectively and sealingly engages with the boss portion to selectively inhibit fluid flow;

a selectively vibrating flow generator having a sharp edge; and

a driving device configured to selectively vibrate the flow generator to create a streaming fluid flow in a direction away from the sharp edge and disengage the flexible portion from the boss portion to open the valve portion to allow fluid flow between the fluid inlet and the fluid outlet.

2. The acoustic streaming valve arrangement of claim 1, wherein the flow generator comprises two nonparallel surfaces forming an angle.

3. The acoustic streaming valve arrangement of claim 2, wherein the two nonparallel surfaces converge to form the sharp edge.

4. The acoustic streaming valve arrangement of claim 2, wherein the sharp edge has an angle of 90 degrees or less.

5. The acoustic streaming valve arrangement of claim 1, wherein the driving device is configured to vibrate the flow generator at the resonance frequency of the flow generator.

6. The acoustic streaming valve arrangement of claim 1, further comprising a flexible portion deflectable by streaming fluid flow to open a valve.

7. An implantable glaucoma drainage system, comprising:

an inlet passageway and an outlet passageway; and

a valve portion disposed between the inlet and outlet passageways to regulate the passage of fluid from the inlet passageway to the outlet passageway, the valve portion comprising an acoustic streaming valve arrangement configured to open or close the valve portion, the valve portion further comprising a flexible portion deflectable from a neutral condition to a displaced condition, the valve portion allowing passage of fluid when the flexible portion is in a deflected condition and inhibiting passage of fluid when the flexible point is a neutral condition, the inhibiting caused by sealingly engaging the flexible portion with a boss portion.

8. The implantable glaucoma drainage system of claim 7, wherein the acoustic streaming valve arrangement comprises a flow generator and a driving device configured to vibrate the flow generator, the flow generator being disposed in the inlet passageway.

9. The implantable glaucoma drainage system of claim 7, wherein the flow generator comprises two nonparallel surfaces forming an angle.

10. The implantable glaucoma drainage system of claim 9, wherein the two nonparallel surfaces converge to form a sharp edge.

11. The implantable glaucoma drainage system of claim 10, wherein the sharp edge has an angle of 90 degrees or less.

12. The implantable glaucoma drainage system of claim 10, wherein the sharp edge is an extending edge.

13. The implantable glaucoma drainage system of claim 7, wherein the flexible portion is a membrane.

14. The implantable glaucoma drainage system of claim 7, wherein the acoustic streaming valve arrangement comprises a flow generator and a driving device configured to vibrate the flow generator, the flow generator being disposed in a chamber adjacent the inlet passageway.

15. The implantable glaucoma drainage system of claim 14, wherein the driving device is implantable with the flow generator.

16. A method comprising:

implanting a flow system in an eye of a patient; and

activating an acoustic streaming valve arrangement forming a part of the flow system to open or close a valve portion to inhibit or allow drainage fluid to flow through the flow system, wherein opening the valve portion includes causing it to disengage from a boss portion.

17. The method of claim 16, wherein activating an acoustic streaming valve arrangement comprises placing a driving device in the proximity of the flow system to induce vibration in a flow generator of the acoustic streaming valve arrangement.

18. The method of claim 17, wherein activating an acoustic streaming valve arrangement comprises placing the driving device in contact with the flow system to induce vibration in the flow generator.

19. The method of claim 16, comprising deflecting a flexible portion of the flow system with the acoustic streaming valve arrangement to inhibit or allow drainage fluid to flow through the flow system.