Buccal bioadhesive strip and method of treating snoring and sleep apnea
First Claim
1. A buccal bioadhesive strip that when applied to the tissue of the soft palate, stiffens the tissue to reduce vibration, comprising:
- at least one surface of said strip has a pattern defined by a plurality of spaced apart features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 .mu.m in at least a portion of said at least one surface, a strip having a first and second side, the first side having a bioadhesive that is adapted to bind to a mucosal membrane for at least 1 hour while inside a person'"'"'s mouth, wherein said strip extends over a majority of the soft palate,said strip including breath freshening components;
said strip adapted to persist in a mouth of a user for at least 3 hours; and
wherein said strip includes between 0.2 and 0.9% xylitol by weight.
1 Assignment
0 Petitions
Accused Products
Abstract
A method, system and device for addressing the reduction of snoring includes a removable or dissolvable strip of material that adhere to mucosal tissue of a person'"'"'s soft palate to provide stiffening support therefore, thus reducing the occurrence of vibration of such tissue during sleep. Preferred embodiments include of a specially textured surface, either one both or at least the outer side of an adhesive strip (the side facing away from the mucosal tissue to which it is attached) that has anti-microbial characteristics, bioluminescent expressions, etc. and a surface topography that resists bioadhesion of undesired bacteria that are typically present in a human'"'"'s mouth.
-
Citations
20 Claims
-
1. A buccal bioadhesive strip that when applied to the tissue of the soft palate, stiffens the tissue to reduce vibration, comprising:
-
at least one surface of said strip has a pattern defined by a plurality of spaced apart features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 .mu.m in at least a portion of said at least one surface, a strip having a first and second side, the first side having a bioadhesive that is adapted to bind to a mucosal membrane for at least 1 hour while inside a person'"'"'s mouth, wherein said strip extends over a majority of the soft palate, said strip including breath freshening components; said strip adapted to persist in a mouth of a user for at least 3 hours; and wherein said strip includes between 0.2 and 0.9% xylitol by weight. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A buccal bioadhesive strip that when applied to the tissue of the soft palate, stiffens the tissue to reduce vibration, comprising:
at least one surface of said strip has a pattern defined by a plurality of spaced apart features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 .mu.m in at least a portion of said at least one surface. - View Dependent Claims (11, 12)
-
13. A method of treating snoring and/or obstructive sleep apnea in a subject in need of such treatment, comprising:
providing to a subject a buccal bioadhesive strip adapted to bind a mucosal membrane by applying said strip to the subject'"'"'s tissue of the soft palate to stiffen the tissue and to reduce vibration of the tissue, the strip having a first and second side, the first side having a bioadhesive that is adapted to bind to a mucosal membrane for at least 1 hour while inside a person'"'"'s mouth, wherein said strip has at least one layer comprising a polymer and extends over a majority of the soft palate, said second side resisting bioadhesion as compared to said first side and having a textured surface that has an anti-microbial characteristic comprising a textured surface having a topography that resists bioadhesion of bacteria present in a human'"'"'s mouth, and wherein said strip includes at least about 200 mg xylitol and one of bacterial and helminth components, and wherein the strip is porous, biodegradable and does not result in permanent tissue changes that affect the physical characteristics of the soft palate. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
Specification