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BCL-2-like protein 11 SRM/MRM assay

  • US 9,551,719 B2
  • Filed: 07/15/2013
  • Issued: 01/24/2017
  • Est. Priority Date: 01/13/2011
  • Status: Active Grant
First Claim
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1. A method for measuring the level of the human Bcl-2-like protein 11 (BIM) in a human biological sample of formalin-fixed tissue, comprising detecting and quantifying the amount of a BIM fragment peptide in a protein digest prepared from said biological sample using mass spectrometry;

  • and calculating the amount of BIM protein in said sample;

    wherein the BIM fragment peptide consists of the peptide of SEQ ID NO;

    2 andwherein said level is a relative level or an absolute level.

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