Method and apparatus for reshaping a ventricle

• US 9,561,105 B2
• Filed: 10/27/2014
• Issued: 02/07/2017
• Est. Priority Date: 10/04/2006
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Rowe, Stanton J.
• Primary Examiner(s): Sevilla, Christian
• Assistant Examiner(s): Mathew, Seema
• Application Number:
  US14/524,950
• Publication Number:
  US 20150045878A1
• Time in Patent Office: 834 Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2466 Delivery devices therefor
• CPC Class Codes: A61F 2/2481 Devices outside the heart wall, e.g. bags, strips or bands
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2230/0041 J-shaped

Abstract

Methods are provided for reshaping the left ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient'"'"'s vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the implantable body applies a longitudinal (downward) force against the inner surface of the left ventricle, thereby causing the left ventricle to distend or elongate downwardly. The implantable body preferably includes an anchor which is deployed adjacent the mitral valve for maintaining the longitudinal force against the inner surface of the left ventricle.

Claims

1. A method of improving the function of a patient'"'"'s heart, comprising:

delivering an implantable body into a left ventricle by a delivery catheter;

the implantable body comprising an anchor coupled to an elongate pusher member;

applying a force at the base of the left ventricle by causing the elongate pusher member to push against an inner wall of the left ventricle;

deploying the anchor adjacent a mitral valve for securing the elongate pusher member in the left ventricle and removing the delivery catheter from the heart while leaving the implantable body in the left ventricle;

wherein the pusher member reshapes the left ventricle by permanently elongating the left ventricle in a longitudinal direction for improving the pumping efficiency of the patient'"'"'s heart.

2. The method of claim 1, wherein the implantable body is delivered percutaneously into the left ventricle through the patient'"'"'s vasculature.

3. The method of claim 2, wherein the implantable body is advanced through the patient'"'"'s vasculature while contained in a lumen of a delivery sheath and then deployed in the left ventricle by advancing the implantable body through an open distal end of the delivery sheath.

4. The method of claim 1, wherein the anchor comprises an annular body.

5. The method of claim 4, wherein the annular body is a radially expandable frame.

6. The method of claim 5, wherein a prosthetic valve member is mounted within the radially expandable frame.

7. A method of improving the function of a patient'"'"'s heart, comprising:

delivering an implantable body into the left ventricle by a delivery catheter, the implantable body having an anchor member and an elongate pusher member permanently fixed to the anchor member, the pusher member having a length sized to extend from a mitral valve to an apex of the left ventricle, the anchor member sized for deployment adjacent the mitral valve, the pusher member extending along a longitudinal axis from the anchor member to the apex of the left ventricle, the pusher member having a distal end portion adapted to apply a longitudinal force to an inner surface of the heart at the apex of the left ventricle;

ejecting the implantable body from the delivery catheter;

expanding the anchor member for securing the anchor member adjacent the mitral valve;

deploying the pusher member for applying the longitudinal force to the inner surface at the apex of the left ventricle, thereby permanently elongating the left ventricle and improving a pumping efficiency of the left ventricle; and

removing the delivery catheter from the heart while leaving the implantable body in the left ventricle.

8. The method of claim 7, wherein the anchor member comprises a radially expandable stent having an unobstructed lumen extending therethrough.

9. The method of claim 8, wherein a prosthetic valve member is mounted within the radially expandable stent.

10. A method of improving the function of a patient'"'"'s heart, comprising:

delivering an implantable body into a left ventricle by a delivery catheter;

applying a longitudinal pushing force against an inner surface at a base of the left ventricle, thereby elongating the left ventricle in a longitudinal direction and removing the delivery catheter from the heart while leaving the implantable body in the left ventricle;

wherein the implantable body applies the longitudinal pushing force against the inner surface at the base of the left ventricle, the implantable body comprising an expandable frame coupled to an elongate pusher member;

wherein the expandable frame is anchored to the mitral valve for maintaining the longitudinal pushing force against the inner surface at the base of the left ventricle and wherein the left ventricle is permanently elongated in the longitudinal direction after the implantable body is deployed.

11. The method of claim 10, wherein a distal end of the pusher member comprises an elongate J-shape that extends along a linear course from the frame to the apex portion, wherein a distal end of the pusher member comprises a flexible, atraumatic tip portion that approximates the apex portion.