Techniques for placing medical leads for electrical stimulation of nerve tissue

• US 9,561,369 B2
• Filed: 11/20/2012
• Issued: 02/07/2017
• Est. Priority Date: 04/30/2008
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Morris, Mary M, Klepfer, Ruth N, Burnes, John E, Bonner, Matthew David, Hill, Michael R. S., Scheiner, Avram
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US13/681,536
• Publication Number:
  US 20130150939A1
• Time in Patent Office: 1,540 Days
• Field of Search: 607115-117, 607/132
• US Class Current: 1/1
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/057 Anchoring means; Means for fixing the head inside the heart
• CPC Class Codes: A61N 1/36053 adapted for vagal stimulation A61N1/36114 takes precedence
• CPC Class Codes: A61N 1/36085 Eating disorders or obesity
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36128 Control systems

Abstract

This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

Claims

1. A system configured to deliver electrical stimulation to a patient'"'"'s vagus nerve, the system comprising a delivery catheter and a deployment member extendable and retractable from a lumen of the catheter, the deployment member including a guidewire, at least one electrode, and a tubular member, the at least one electrode being connected to a distal portion of an implantable medical lead, the lead being advanceabie over the guidewire, and the tubular member including a lumen in which the lead and the guidewire are received such that the lead and the guidewire are advanceable therein;

and

wherein;

one or both of the tubular member and the guide wire is constructed of a shape memory material to take on an S-shape when the deployment member is advanced out from the lumen of the catheter; and

the S-shape is configured to span a well of a vein adjacent to the vagus nerve, when the deployment member extends through the wall.

2. The system of claim 1, further comprising another implantable medical lead, and an implantable medical device for connection to the implantable medical leads, the implantable medical device including a cardiac therapy module and a neurostimulation module, the cardiac therapy module to monitor electrical activity of the patient'"'"'s heart via one or more electrodes of the other implantable medical lead, and the neurostimulation module to generate stimulation signals delivered by the at least one electrode of the deployment member.

3. The system of claim 1 further comprising a physiologic feedback sensor connected to the delivery catheter.

4. The system of claim 1, further comprising an imaging system sensor connected to the delivery catheter.

5. A system configured to deliver electrical stimulation to a patient'"'"'s vague nerve, the system comprising a delivery catheter and a deployment member extendable and retractable from a Lumen of the catheter, the deployment member including a guidewire, at least one electrode, and a tubular member, the at least one electrode being connected to a distal portion of an implantable medical lead the lead being advanceable over the guidewire, and the tubular member including a lumen in which the lead and the guidewire are received such that the lead and the guidewire are advanceable therein;

and wherein;

one or both of the tubular member and the guide wire is constructed of a share memory material to take on an S-shape when the deployment member is advanced out from the lumen of the catheter; and

the S-shape is configured to span a wall of a vein adjacent to the vagus nerve, when the deployment member extends through the wall,

wherein;

the tubular member is constructed of the shape memory material to take on the S-shape; and

the tubular member is a needle configured to pierce through the wall of the vein.

6. The system of claim 5, wherein:

the guidewire is constructed of the shape memory material to take on the S-shape;

the S-shape is configured to also span the vagus nerve, when the deployment member extends through the wall; and

the at least one electrode comprises a first electrode and a second electrode, the first and second electrodes being spaced apart from one another along the distal portion of the lead such that the first electrode is located at a proximal end of the S-shape, within the vein, and the second electrode is located at a distal end of the S-shape, outside the vein and on an opposite side of the vagus nerve from the vein, when the deployment member extends through the wall of the vein.

7. The system of claim 6, further comprising an implantable medical device for connection to the implantable medical lead, the implantable medical device including a signal generator to couple and energize the first and second electrodes in an anode-cathode combination.