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Systems for handling microfludic droplets

DC
  • US 9,562,837 B2
  • Filed: 04/02/2013
  • Issued: 02/07/2017
  • Est. Priority Date: 05/11/2006
  • Status: Active Grant
First Claim
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1. An assembly, the assembly comprising:

  • a microchannel in a horizontal plane;

    at least one droplet formation module comprising a sample inlet, an immiscible fluid inlet, and a junction, wherein the junction is located between the sample inlet and the microchannel and the droplet formation module is configured to produce droplets comprising the sample surrounded by the immiscible fluid; and

    at least one downstream separation chamber comprising a droplet receiving chamber inlet and at least one droplet receiving outlet, wherein the separation chamber is upright to the microchannel and out of the horizontal plane;

    wherein the droplet formation module and the separation chamber are in fluid communication with each other via the microchannel; and

    wherein the separation chamber has a wider cross-section than the microchannel cross-section to accumulate a plurality of droplets comprising the sample and is of a volume sufficient to separate the plurality of droplets comprising the sample from the immiscible fluid within the separation chamber.

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