Method and sysem for non-ablative acne treatment and prevention
First Claim
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1. A method for treating acne in a skin of a subject, the method comprising:
- a) identifying a sebaceous gland in a portion of the skin having the acne with ultrasound imaging; and
b) delivering an ultrasound energy from a transducer probe to the sebaceous gland, the ultrasound energy configured to generate an elevated temperature in the sebaceous gland for a predetermined length of time, wherein the predetermined length of time allows a decrease of sebum and sebum production and does not allow ablation or coagulation of tissue within the sebaceous gland at the elevated temperature to treat existing acne and prevent future acne from developing.
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Abstract
A method and system for non-ablative acne treatment and prevention is disclosed. The method utilizes ultrasound energy which is targeted at a region of interest to treat existing acne and prevent future acne from forming. The application of ultrasound energy causes numerous physiological effects that treat acne. Some of these physiological effects comprise reducing sebum, increasing perfusion at the region of interest, denaturing proteins at the region of interest, creating an uninhabitable environment at the region of interest, initiating programmed cell death at the region of interest and the initiation of mechanical effects at the region of interest.
840 Citations
20 Claims
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1. A method for treating acne in a skin of a subject, the method comprising:
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a) identifying a sebaceous gland in a portion of the skin having the acne with ultrasound imaging; and b) delivering an ultrasound energy from a transducer probe to the sebaceous gland, the ultrasound energy configured to generate an elevated temperature in the sebaceous gland for a predetermined length of time, wherein the predetermined length of time allows a decrease of sebum and sebum production and does not allow ablation or coagulation of tissue within the sebaceous gland at the elevated temperature to treat existing acne and prevent future acne from developing. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method for treating acne in a skin of a subject, the method comprising:
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a) identifying a pilosebaceous tissue in a portion of the skin having the acne with ultrasound imaging, the pilosebaceous tissue containing at least one bacterium associated with the acne; and b) delivering an ultrasound energy from a transducer probe to the pilosebaceous tissue, the ultrasound energy configured to generate an elevated temperature in the pilosebaceous tissue for a predetermined length of time, wherein the predetermined length of time initiates programmed cell death in the at least one bacterium and does not allow ablation or coagulation of tissue within the pilosebaceous tissue at the elevated temperature to treat existing acne and prevent future acne from developing. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15)
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16. A method for treating acne in a skin of a subject, the method comprising:
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a) identifying a pilosebaceous tissue in a portion of the skin having the acne with ultrasound imaging; b) delivering an unfocused ultrasound energy from a transducer probe to the pilosebaceous tissue; c) sensing, using a sensor configured to sense an amount of ultrasound energy transferred to the pilosebaceous tissue, an amount of the unfocused ultrasound energy transferred to the pilosebaceous tissue; and d) in response to sensing that the amount of the unfocused ultrasound energy transferred to the pilosebaceous tissue has exceeded a predetermined threshold, stopping the delivering the unfocused ultrasound energy, wherein the predetermined threshold allows a physiological effect in the pilosebaceous tissue and does not allow ablation and coagulation of tissue within the pilosebaceous tissue to treat existing acne and prevent future acne from developing, wherein the physiological effect is selected from the group consisting of; increased blood perfusion; denaturing of proteins; inhibition of sebum production; and programmed cell death. - View Dependent Claims (17, 18, 19, 20)
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Specification