Hydrogel jacketed stents
First Claim
1. A jacketed stent for placement in a bodily vessel comprising a stent frame having an inner surface, an exterior surface, an extended configuration and an un-extended diameter, the jacketed stent having a hydrogel sheet associated with the exterior surface such that the hydrogel sheet forms a tubular jacket over and around a circumference of the stent frame upon extension of the stent frame to its extended configuration, wherein the stent frame is non-self extendable, wherein the hydrogel sheet has a thickness and comprises polyurethanes, polyacrylic acid and esters thereof, polymethacrylic acid and esters thereof, polyacrylonitrile, polyethylene glycol and derivatives thereof, polyacrylamide, epoxy polymers, copolymers thereof or mixtures thereof, wherein the hydrogel sheet is configured to swell when placed in water to a swollen state in which the hydrogel sheet at least partially covers the inner surface of the stent frame in the extended configuration in water and wherein the jacketed stent has an open inner lumen and wherein the hydrogel sheet has an un-hydrated thickness from 0.05 mm to 0.3 mm.
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Accused Products
Abstract
Hydrogel jacketed stents provide the ability to fill in the stent frame in vivo to at least partially cover the interior of the surface of the stent following deployment while having the convenience of attaching the jacket to the exterior of the stent. The hydrogel can be pleated and/or folder over the exterior of the stent to provide for extension of the stent without damaging the hydrogel. The hydrogel sheet can be secured at one or more points along the circumference to associate the sheet of hydrogel with the exterior surface of the stent frame. The stent can be conveniently delivered using similar technology as conventional stents if desired. The hydrogel can provide for drug delivery if desired.
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Citations
25 Claims
- 1. A jacketed stent for placement in a bodily vessel comprising a stent frame having an inner surface, an exterior surface, an extended configuration and an un-extended diameter, the jacketed stent having a hydrogel sheet associated with the exterior surface such that the hydrogel sheet forms a tubular jacket over and around a circumference of the stent frame upon extension of the stent frame to its extended configuration, wherein the stent frame is non-self extendable, wherein the hydrogel sheet has a thickness and comprises polyurethanes, polyacrylic acid and esters thereof, polymethacrylic acid and esters thereof, polyacrylonitrile, polyethylene glycol and derivatives thereof, polyacrylamide, epoxy polymers, copolymers thereof or mixtures thereof, wherein the hydrogel sheet is configured to swell when placed in water to a swollen state in which the hydrogel sheet at least partially covers the inner surface of the stent frame in the extended configuration in water and wherein the jacketed stent has an open inner lumen and wherein the hydrogel sheet has an un-hydrated thickness from 0.05 mm to 0.3 mm.
- 15. A jacketed stent comprising a stent frame having an outer surface, an inner surface and an un-extended diameter, the jacketed stent having a hydrogel sheet associated with the outer surface of the stent frame, wherein the hydrogel sheet is folded to accommodate a larger surface area of the hydrogel sheet relative to the outer surface of the stent frame and comprises polyurethanes, polyacrylic acid and esters thereof, polymethacrylic acid and esters thereof, polyacrylonitrile, polyethylene glycol and derivatives thereof, polyacrylamide, epoxy polymers, copolymers thereof or mixtures thereof and wherein the stent frame deploys to an extended configuration with the hydrogel sheet stretched along the outer surface of the stent frame and wherein the hydrogel sheet has a dry thickness from about 0.05 mm to about 0.3 mm and wherein the hydrogel sheet is configured to swell when placed in water.
Specification