Helical graft

• US 9,572,694 B2
• Filed: 04/18/2014
• Issued: 02/21/2017
• Est. Priority Date: 03/18/2003
• Status: Active Grant

• Current Assignee: Veryan Medical Limited
• Original Assignee: Veryan Medical Limited
• Inventors: Caro, Colin G., Watkins, Nicholas V., Sherwin, Spencer J.
• Primary Examiner(s): Sevilla, Christian
• Assistant Examiner(s): Mathew, Seema
• Application Number:
  US14/256,604
• Publication Number:
  US 20140225304A1
• Time in Patent Office: 1,040 Days
• Field of Search: 623/1.22
• US Class Current: 1/1
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: B29C 53/14 Twisting for textile fibres D01H
• CPC Class Codes: B29C 65/00 Joining or sealing of preformed parts , e.g. welding of plastics materials; Apparatus therefor general aspects of processes or apparatus for joining preformed parts B29C66/00; using porous material formed by internal pressure generated therein for joining preformed parts B29C44/1228, B29C44/326

Abstract

A graft includes a flow tubing having a tubing portion defining a flow lumen. The flow lumen of the tubing portion is substantially free of ribs or grooves. A center line of the flow lumen follows a substantially helical path with a helix angle less than or equal to 65°. The amplitude of the helix is less than or equal to one half of the internal diameter of the tubing portion.

Claims

1. A method of inhibiting flow instability in a graft for biomedical use, the graft comprising flow tubing which is for use in vivo to carry blood and which is made of biocompatible material, the flow tubing having a tubing portion with an internal diameter and defining a flow lumen, wherein the flow lumen of the tubing portion is of circular cross-section, the flow lumen of said tubing portion having a centre line and being substantially free of ribs or grooves, wherein the graft is thermally set such that it retains a twisted shape and the centre line of the flow lumen follows a helical path about a longitudinal axis so as to define a helical center line, the helical center line having a helix angle and a helix amplitude, the helix angle being less than or equal to 45°

, and the helix amplitude being less than or equal to one half of the internal diameter of the tubing portion, and wherein the flow tubing is flexible and is capable of adopting a configuration in which the longitudinal axis is curved and the helical center line of the tubing portion follows a helical path about the curved longitudinal axis.

2. A method as claimed in claim 1, wherein the amplitude of the helical center line divided by the internal diameter of the tubing is at least 0.05.

3. A method as claimed in claim 1, wherein the helix angle is less than or equal to 15°

.

4. A method as claimed in claim 1, wherein the centre line of the tubing portion follows a substantially helical path about an axis which is curved.

5. A method as claimed in claim 1, wherein the graft further comprises a pharmaceutical coating.

6. A method as claimed in claim 1, wherein the tubing portion comprises a tubular wall which resists reduction of the amplitude of the helical centre line.

7. A method as claimed in claim 1, wherein the graft is thermally shape set.

8. A method as claimed in claim 1, wherein the tubing portion has a wall comprising a helical winding to help maintain a circular cross-section of the flow lumen.

9. A method as claimed in claim 8, wherein the helix angle of the helical winding is larger than the helix angle of the helical centre line of the flow lumen.

10. A method as claimed in claim 1, wherein the graft comprises ePTFE.

11. A method of inhibiting flow instability in a graft for biomedical use, the graft comprising flow tubing which is for use in vivo to carry blood and which is made of biocompatible material, the flow tubing having a tubing portion with an internal diameter and defining a flow lumen, wherein the flow lumen of the tubing portion is of circular cross-section, wherein the graft is thermally set such that it retains a twisted shape and the center line of the flow lumen follows a helical path about a longitudinal axis so as to define a helical center line, the helical center line having a helix angle and, a helix amplitude, the helix angle being less than or equal to 45°

, the helix amplitude being less than or equal to one half of the internal diameter of the tubing portion, and the amplitude of the helical centre line divided by the internal diameter of the tubing portion is at least 0.05, and wherein the flow tubing is flexible and is capable of adopting a configuration in which the longitudinal axis is curved and the helical center line of the tubing portion follows a helical path about the curved longitudinal axis.

12. A method as claimed in claim 11, wherein the helix angle is less than or equal to 15°

.

13. A method as claimed in claim 11, wherein the center line of the tubing portion follows a substantially helical path about an axis which is curved.

14. A method as claimed in claim 11, wherein the graft further comprises a pharmaceutical coating.

15. A method as claimed in claim 11 wherein the tubing portion comprises a tubular wall which resists reduction of the amplitude of the helical center line.

16. A method as claimed in claim 11, wherein the graft is thermally shape set.

17. A method as claimed in claim 11, wherein the tubing portion has a wall comprising a helical winding to help maintain a circular cross-section of the flow lumen.

18. A method as claimed in claim 11, wherein the helix angle of the helical winding is larger than the helix angle of the helical center line of the flow lumen.

19. A method as claimed in claim 11, wherein the graft comprises ePTFE.