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Methods and compositions for prevention or treatment of a disease

  • US 9,574,211 B2
  • Filed: 05/13/2015
  • Issued: 02/21/2017
  • Est. Priority Date: 05/13/2014
  • Status: Active Grant
First Claim
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1. A fusion molecule comprising (i) an engineered nuclease that binds to a target site within SEQ NOs:

  • 3, 4, 5 or 6 of an endogenous gene that produces a microRNA (miRNA), and (ii) a cleavage domain.

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