Axial lengthening thrombus capture system
First Claim
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1. A clot capture system, comprising:
- a first, outer tubular shaft comprising a central lumen, the first outer tubular shaft comprising a proximal portion and a distal portion, the distal portion more radially expandable than the proximal portion;
a second tubular shaft configured to be positioned within the central lumen of the first shaft;
a third tubular shaft configured to be positioned within a central lumen of the second shaft;
a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having a proximal-facing opening and a ring-shaped capture guide attached to a circumference of the proximal-facing opening, the capture guide operably attached to the second tubular shaft, the second end attached to an outer wall of the third tubular shaft,wherein the shape memory tubular body is compressed within the central lumen of the second tubular shaft in a first delivery configuration,wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide are radially expanded but the second end and a majority of the shape memory tubular body remains radially compressed within the central lumen of the second tubular shaft and the second end is positioned proximal to the first end and the shape memory tubular body has a first expanded axial length,wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the shape memory tubular body along its second expanded axial length is substantially the same as a width of the shape memory tubular body along its first expanded axial length,wherein the first tubular shaft is configured to be reversibly coupled with respect to the second tubular shaft in the first delivery configuration and axially movable with respect to the third tubular shaft in the second configuration.
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Abstract
Axial lengthening thrombus capture systems and methods can remove materials of interest, including blood clots, from a body region. These can involve the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.
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Citations
25 Claims
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1. A clot capture system, comprising:
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a first, outer tubular shaft comprising a central lumen, the first outer tubular shaft comprising a proximal portion and a distal portion, the distal portion more radially expandable than the proximal portion; a second tubular shaft configured to be positioned within the central lumen of the first shaft; a third tubular shaft configured to be positioned within a central lumen of the second shaft; a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having a proximal-facing opening and a ring-shaped capture guide attached to a circumference of the proximal-facing opening, the capture guide operably attached to the second tubular shaft, the second end attached to an outer wall of the third tubular shaft, wherein the shape memory tubular body is compressed within the central lumen of the second tubular shaft in a first delivery configuration, wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide are radially expanded but the second end and a majority of the shape memory tubular body remains radially compressed within the central lumen of the second tubular shaft and the second end is positioned proximal to the first end and the shape memory tubular body has a first expanded axial length, wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the shape memory tubular body along its second expanded axial length is substantially the same as a width of the shape memory tubular body along its first expanded axial length, wherein the first tubular shaft is configured to be reversibly coupled with respect to the second tubular shaft in the first delivery configuration and axially movable with respect to the third tubular shaft in the second configuration. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A clot capture system, comprising:
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a first, outer tubular shaft comprising a central lumen; a second tubular shaft configured to be positioned within the central lumen of the first, outer tubular shaft, the second tubular shaft comprising a proximal portion and a distal portion, the distal portion more radially expandable than the proximal portion; a third tubular shaft configured to be positioned within a central lumen of the second tubular shaft; a tubular mesh comprising a first end, a second end, and an axial length therebetween, the first end having a proximal-facing opening and a ring-shaped capture guide attached to a circumference of the proximal-facing opening, the capture guide operably attached to the second tubular shaft, the second end attached to an outer wall of the third tubular shaft, wherein the tubular mesh is compressed within the central lumen of the second tubular shaft in a delivery configuration, wherein the tubular mesh is transformable to a second configuration in which the first end and the capture guide is radially expanded but the second end and a majority of the tubular mesh remains radially compressed within the central lumen of the second tubular shaft and the second end is positioned proximal to the first end and the tubular mesh has a first expanded axial length, wherein the tubular mesh is transformable to a third configuration in which the tubular mesh has a second expanded axial length greater than the first expanded axial length, wherein a width of the tubular mesh along its second expanded axial length is substantially the same as a width of the tubular mesh along its first expanded axial length, wherein the third tubular shaft extends distally through the proximal-facing opening as well as the second axial expanded length of the tubular mesh.
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22. A clot capture system, comprising:
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a first, outer tubular shaft comprising a central lumen; a second tubular shaft configured to be positioned within the central lumen of the first, outer tubular shaft, the second tubular shaft comprising a proximal portion and a distal portion, the distal portion more radially expandable than the proximal portion; a third tubular shaft configured to be positioned within a central lumen of the second tubular shaft; a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having a proximal-facing opening and a ring-shaped capture guide attached to a circumference of the proximal-facing opening, the capture guide operably attached to the second tubular shaft via a sleeve circumscribing a portion of the second tubular shaft, the second end attached to an outer wall of the third tubular shaft, wherein the shape memory tubular body is compressed within the central lumen of the second tubular shaft in a delivery configuration, wherein the shape memory tubular body is transformable to a second configuration by axial movement of the second tubular shaft with respect to the first tubular shaft, in which the first end and the capture guide is radially expanded but the second end and a segment of the shape memory tubular body remains radially compressed within the central lumen of the second tubular shaft and the second end is positioned proximal to the first end and the shape memory tubular body has a first expanded axial length, wherein the shape memory tubular body is transformable to a third configuration by movement of the second tubular shaft with respect to the third tubular shaft, in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the shape memory tubular body along its second expanded axial length is substantially the same as a width of the shape memory tubular body along its first expanded axial length, wherein the third tubular shaft extends distally through the proximal-facing opening as well as the second axial expanded length of the shape memory tubular body. - View Dependent Claims (23, 24, 25)
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Specification