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Methods and device to neutralize soluble toxic agents in the brain

  • US 9,580,494 B2
  • Filed: 05/22/2015
  • Issued: 02/28/2017
  • Est. Priority Date: 05/14/2007
  • Status: Active Grant
First Claim
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1. A method for clearing cerebral vascular amyloid plaques in a subject in need thereof, comprising:

  • chronically delivering to a cerebral ventricle of the subject an anti-Aβ

    antibody in an amount effective to clear the cerebral vascular amyloid plaques,wherein the anti-Aβ

    antibody is chronically delivered to the subject'"'"'s cerebral ventricle from a reservoir of an implantable infusion device.

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