Materials for disinfection produced by non-thermal plasma

• US 9,585,390 B2
• Filed: 08/03/2011
• Issued: 03/07/2017
• Est. Priority Date: 08/03/2010
• Status: Active Grant

• Current Assignee: Drexel University
• Original Assignee: Drexel University
• Inventors: Rabinovich, Alexander, Fridman, Gregory, Park, Sin, Shainsky, Natalie, Dobrynin, Danil V., Friedman, Gennady, Fridman, Alexander, Cooper, Moogega, Brooks, Ari D., Joshi, Suresh G., Poor, Alexander E., Ercan, Utku K., Ingerman, Mark
• Primary Examiner(s): Yoo, Regina M
• Application Number:
  US13/813,750
• Publication Number:
  US 20150038584A1
• Time in Patent Office: 2,043 Days
• US Class Current: 1/1
• CPC Class Codes: A01N 25/02 containing liquids as carriers, diluents or solvents
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 37/30 containing the groups —CO—N< and , both being directly attached by their carbon atoms to the same carbon skeleton, e.g. H2N—NH—CO—C6H4—COOCH3; Thio-analogues thereof
• CPC Class Codes: A01N 37/46 N-acyl derivatives
• CPC Class Codes: A01N 43/16 with oxygen as the ring hetero atom
• CPC Class Codes: A01N 61/00 Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• CPC Class Codes: A61L 2/0011 using physical methods
• CPC Class Codes: A61L 2/14 Plasma, i.e. ionised gases
• CPC Class Codes: A61L 2/16 using chemical substances
• CPC Class Codes: A61L 2/22 Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps

Abstract

Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection composition, wherein the disinfection composition is a liquid, and contacting a surface with the disinfection composition, wherein the surface is at least partially disinfected upon contact with the disinfection composition. Additional aspects of the present subject matter are directed to a method comprising forming a disinfection composition by contacting an organic material with a non-thermal plasma, wherein the disinfection composition is a liquid. A further aspect of the present subject matter is directed to a disinfection composition comprising an organic material contacted by a non-thermal plasma, wherein the disinfection composition is a liquid.

Claims

1. A method comprising:

contacting an aqueous composition, the aqueous composition being an aqueous gel or water containing an organic material comprising an amino acid, with a plasma to form a disinfection composition, wherein the plasma is a dielectric barrier discharge, a corona or pulsed corona discharge, arc, spark, gliding arc, radio frequency discharge, or microwave discharge plasma.

2. The method of claim 1, wherein the aqueous composition is water, and the water is in the form of an aerosol or mist.

3. The method of claim 1, wherein the aqueous composition is water, and the water contains a saline or phosphate buffer composition, or a combination thereof.

4. The method of claim 1, wherein the aqueous composition is an aqueous gel, and the aqueous gel is an alginate gel.

5. The method of claim 1, wherein the aqueous composition is water, and the organic material comprises N-Acetyl Cysteine.

6. The method of claim 1, further comprising removing at least part of the water from the disinfection composition to form a dehydrated disinfection composition.

7. The method of claim 6, further comprising reconstituting the dehydrated disinfection composition to form a reconstituted disinfection composition.

8. The method of claim 7, further comprising the step of contacting the disinfection composition with a new surface, said surface being at least partially disinfected upon contact with the reconstituted disinfection composition.

9. The method of claim 1, further comprising the step of contacting the disinfection composition with a surface, said surface being at least partially disinfected upon contact with the disinfection composition.

10. The method of claim 9, wherein the surface comprises metal, plastic, glass, ceramic, a composite thereof, or a living tissue.

11. The method of claim 9, wherein the surface is contacted with the disinfection composition remote from the plasma.

12. The method of claim 9, wherein a period of time elapses between forming the disinfection composition and contacting the disinfection composition with the surface.

13. A disinfection composition prepared by the method of claim 1, prepared by contacting the aqueous gel or water containing an organic material comprising an amino acid with a plasma, wherein the plasma is a dielectric barrier discharge, a corona or pulsed corona discharge, arc, spark, gliding arc, radio frequency discharge, or microwave discharge plasma, wherein the disinfection composition is capable of at least partially disinfecting a surface.

14. A composition prepared by the method of claim 6.

15. The composition of claim 14, wherein the dehydrated disinfection composition is a powder.

16. A composition wherein the composition of claim 14 is reconstituted to form a liquid, aerosol, or both.

17. A product containing the disinfection composition claim 13, wherein the disinfection composition is provided on a woven or non-woven fabric.