Multiple layer filamentary devices for treatment of vascular defects

• US 9,585,669 B2
• Filed: 05/11/2012
• Issued: 03/07/2017
• Est. Priority Date: 04/21/2008
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Becking, Frank P., Rosqueta, Arturo S., Loganathan, Siddharth
• Primary Examiner(s): Yabut, Diane
• Assistant Examiner(s): Ton, Martin T
• Application Number:
  US13/470,013
• Publication Number:
  US 20120316598A1
• Time in Patent Office: 1,761 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00862 elastic or resilient for sutures A61B2017/0618
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2018/00416 Treatment of aneurisms
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: Y10T 156/1051 by folding

Abstract

Braid-balls suitable for aneurysm occlusion and/or parent vessel occlusion/sacrifice (e.g., in treating neurovascular defects) are disclosed. Especially for aneurysm treatment, but also for either one of the aforementioned treatments, the form of the ball is very important. In particular, the density of the device is paramount in applications where braid itself is intended to moderate or stop blood flow—allowing thrombosis within a volume formed by the ball.

Claims

1. A method of treating a patient, comprising:

providing a device for treatment of a patient'"'"'s vasculature, comprising;

a self-expanding resilient permeable shell having a proximal end, a distal end, a longitudinal axis and further including a plurality of elongate resilient filaments with a woven structure secured relative to each other at proximal ends and distal ends thereof, a radially constrained elongated state configured for delivery within a microcatheter, and an expanded relaxed state with a globular configuration relative to the radially constrained elongated state, and an inner structure of filamentary members disposed within an interior volume of the resilient permeable shell and secured to the permeable shell at an end thereof, the inner structure including a plurality of elongate resilient filaments with a woven structure secured relative to each other at least at the proximal ends thereof, which has a radially constrained elongated state which is shorter than the permeable shell in its radially constrained state and which has an expanded relaxed state relative to the radially constrained state;

advancing the device to a treatment site within a patient'"'"'s vasculature in a constrained elongated state; and

deploying the device within a vascular defect at the treatment site within the patient'"'"'s vasculature such that the permeable shell and inner structure self-expand to their respective expanded states.

2. The method of claim 1, wherein the filaments of at least one of either the permeable shell or the inner structure comprise at least two different transverse dimensions.

3. A self-expanding implant for treating a patient'"'"'s vasculature, the implant comprising:

a resilient, permeable shell having proximal and distal end portions, an interior volume, a longitudinal axis, and a plurality of elongate, woven filaments secured relative to each other at proximal end portions and distal end portions thereof, the shell having a radially constrained, elongated state configured for delivery within a microcatheter and an expanded state relative to its radially constrained, elongated state; and

an inner structure, disposed within the shell interior volume, comprising a plurality of elongate, woven filaments and being secured to the shell at the proximal end portion thereof, the inner structure having a radially constrained, elongated state shorter than the radially constrained, elongated state of the shell, the inner structure having an expanded state relative to its radially constrained, elongated state, wherein when the shell and the inner structure self-expand to their respective expanded states, a free, unsecured end portion of the inner structure is longitudinally separated from an inner surface of the shell distal end portion by an internal gap.

4. The device of claim 3, wherein the inner structure filaments are secured at the distal end portion thereof to form an inner hub.

5. The device of claim 3, wherein filaments of the inner structure comprise a woven structure forming a substantially enclosed volume.

6. The device of claim 3, wherein the proximal and distal end portions comprise respective proximal and distal hubs, the proximal and distal hubs being disposed exterior to the interior volume and being inset into the interior volume.

7. An embolic device for treatment a patient'"'"'s vasculature, the device comprising:

a braided structure having an interior volume and comprising a plurality of wires that are secured relative to each other at proximal and distal end portions of the structure to form respective proximal and distal hubs, the proximal and distal hubs disposed exterior to the interior volume and being inset into the interior volume, the structure being adapted to (i) compress into a compressed state, in which the proximal and distal hubs are longitudinally separated at a first distance, for delivery through a microcatheter and (ii) self-expand into an expanded shape, in which the proximal and distal hubs are longitudinally separated at a second distance, less than the first distance, upon release from constraint.

8. The embolic device of claim 7, wherein the expanded shape comprises a globular shape.

9. The embolic device of claim 7, wherein the braided structure comprises a single layer.

10. The embolic device of claim 7, wherein the braided structure comprises inner and outer layers.

11. The embolic device of claim 10, wherein a distal end portion of the inner layer is spaced apart from a distal end portion of the outer layer.

12. The embolic device of claim 11, wherein filaments of the inner layer converge to an unsecured, inner hub to form an inner structure, and wherein filaments of the outer layer converge to the distal hub, the inner hub being spaced apart from the distal hub along a longitudinal axis of the device.

13. The embolic device of claim 12, wherein the inner structure and the outer layer meet at the proximal hub.