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Cardiovascular disease treatment and prevention

  • US 9,585,931 B2
  • Filed: 04/04/2016
  • Issued: 03/07/2017
  • Est. Priority Date: 03/13/2013
  • Status: Active Grant
First Claim
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1. A method, comprising:

  • administering, to the skin of a subject having or at risk of atherosclerosis, a composition comprising an effective amount of gonadotropin-releasing hormone (GnRH) and molecular nitric oxide to treat or prevent atherosclerosis, and a carrier having a phosphatidylcholine component entrapping the nitric oxide, wherein the composition is stable at room temperature and wherein the molecular nitric oxide is present within the carrier as a gas or bound by hydrogen or van der Waals forces.

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