System for providing flow-targeted ventilation synchronized to a patients breathing cycle

• US 9,586,018 B2
• Filed: 05/02/2014
• Issued: 03/07/2017
• Est. Priority Date: 01/26/2007
• Status: Active Grant

• Current Assignee: Fisher & Paykel Healthcare Limited
• Original Assignee: Cs Medical, Inc.
• Inventors: Christopher, Kent L., Diehl, Stephanie S.
• Primary Examiner(s): Vasat, Peter S
• Application Number:
  US14/268,234
• Publication Number:
  US 20140238398A1
• Time in Patent Office: 1,040 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/097 Devices for facilitating collection of breath or for directing breath into or through measuring devices
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0434 Cuffs
• CPC Class Codes: A61M 16/0461 Nasoendotracheal tubes
• CPC Class Codes: A61M 16/0465 Tracheostomy tubes; Devices for performing a tracheostomy; Accessories therefor, e.g. masks, filters
• CPC Class Codes: A61M 16/0484 at the distal end
• CPC Class Codes: A61M 16/0486 Multi-lumen tracheal tubes
• CPC Class Codes: A61M 16/0488 Mouthpieces; Means for guiding, securing or introducing the tubes guiding or introducing with laryngoscopes A61B1/267; holding devices on the body A61M25/02
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0672 Nasal cannula assemblies for oxygen therapy
• CPC Class Codes: A61M 16/0816 Joints or connectors
• CPC Class Codes: A61M 16/0833 T- or Y-type connectors, e.g. Y-piece
• CPC Class Codes: A61M 16/085 Gas sampling
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/10 : Preparation of respiratory gases or vapours
• CPC Class Codes: A61M 16/101 : using an oxygen concentrator
• CPC Class Codes: A61M 16/1095 : in the connecting tubes
• CPC Class Codes: A61M 16/12 : by mixing different gases
• CPC Class Codes: A61M 16/125 : Diluting primary gas with ambient air
• CPC Class Codes: A61M 16/16 : Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/161 : with means for measuring the humidity
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2016/0021 : with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 : pressure meter
• CPC Class Codes: A61M 2016/0036 : in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0039 : in the inspiratory circuit
• CPC Class Codes: A61M 2016/1025 : the O2 concentration
• CPC Class Codes: A61M 2202/0208 : Oxygen
• CPC Class Codes: A61M 2202/025 : Helium
• CPC Class Codes: A61M 2202/0275 : Nitric oxide [NO]
• CPC Class Codes: A61M 2205/16 : with back-up system in case of failure
• CPC Class Codes: A61M 2205/18 : with alarm
• CPC Class Codes: A61M 2205/32 : with radio-opaque indicia
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/70 : with testing or calibration facilities
• CPC Class Codes: A61M 2230/005 : Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/202 : partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2230/205 : partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/432 : partial CO2 pressure (P-CO2)

Abstract

A system selectively delivers either breath-synchronized, flow-targeted ventilation (BSFTV) or closed-system positive pressure ventilation (CSPPV) to augment respiration of a patient with a standard tracheal tube. A removable adaptor has a cap that can be removably attached to the proximal connector of the tracheal tube in BSFTV mode, and an inner cannula that extends within the tracheal tube to effectively divide it into two lumens. The adaptor includes a ventilator connector for removably engaging a ventilator hose to deliver air/oxygen through the adaptor and one lumen of the tracheal tube with a flow rate varying over each respiratory cycle in a predetermined waveform synchronized with the patient'"'"'s respiratory cycle to augment the patient'"'"'s spontaneous respiration. The adaptor also includes a port allowing the spontaneously-breathing patient to freely inhale and exhale in open exchange with the atmosphere through the other lumen.

Claims

1. An apparatus configured for selectively delivering oxygen-containing gas to an airway of a patient in either a closed-system positive-pressure ventilation (CSPPV) mode or a breath-synchronized flow-targeted ventilation (BSFTV) mode, said apparatus comprising:

a tracheal tube configured to be inserted into the patient'"'"'s airway and having an inflatable cuff configured to block the patient'"'"'s airway around the tracheal tube;

a ventilator having;

(a) a gas source providing a variable delivery of oxygen-containing gas;

(b) a processor controlling the gas source; and

(c) a hose removably attachable to the tracheal tube configured for delivering the oxygen-containing gas from the gas source through the tracheal tube to the patient in CSPPV mode;

an adaptor for removable attachment to the tracheal tube in BSFTV mode, said adaptor having;

(a) a cap with a first connector for removable attachment to the ventilator hose, and a second connector for removable attachment to the tracheal tube in BSFTV mode; and

(b) an inner cannula extending from the cap that is removably insertable into the tracheal tube to divide the tracheal tube into two lumens, with a first lumen configured for allowing the spontaneously-breathing patient to freely inhale and exhale in open exchange with the atmosphere through the tracheal tube and adaptor; and

a sensor monitored by the processor and configured for detecting a physical property of the patient'"'"'s respiratory cycle in the first lumen; and

said processor configured to selectively control the gas source to operate in either;

(a) the BSFTV mode, with the adaptor attached to the tracheal tube and ventilator hose, wherein the gas source delivers a flow of oxygen-containing gas through the adaptor cap and the second lumen of the tracheal tube to augment the patient'"'"'s spontaneous respiration, said delivered flow varying over each inspiratory and expiratory phase of the respiratory cycle in a predetermined non-constant flow waveform synchronized with the respiratory cycle to augment the patient'"'"'s spontaneous respiration having;

(i) a positive flow accelerating at the onset of the patient'"'"'s inspiratory phase at a flow rate sufficient to significantly mitigate the airway pressure the patient must generate during spontaneous breathing and thereby reduce the patient'"'"'s work of breathing; and

(ii) a positive flow during at least the early portion of the patient'"'"'s expiratory phase at a flow rate sufficient to significantly mitigate the airway pressure the patient must generate during spontaneous breathing and thereby reduce the patient'"'"'s work of breathing, and to wash carbon dioxide from the patient'"'"'s airway;

said delivered flow allowing the patient to freely inhale and exhale in open exchange with the atmosphere through the first lumen of the tracheal tube and adaptor; and

(b) the CSPPV mode, with the ventilator hose attached to the tracheal tube without the adaptor inserted, wherein the gas source delivers oxygen-containing gas through the tracheal tube to provide positive-pressure ventilation to the patient.

2. The apparatus of claim 1 wherein the sensor is attached to the inner cannula.

3. The apparatus of claim 1 further comprising a gas sampling tube extending along the inner cannula to the sensor.

4. The apparatus of claim 1 wherein the sensor comprises a pressure transducer.

5. The apparatus of claim 1 wherein the sensor comprises a flow sensor.

6. The apparatus of claim 1 wherein the sensor comprises a thermistor.

7. The apparatus of claim 1 wherein the sensor comprises a carbon dioxide sensor.

8. The apparatus of claim 1 wherein one lumen is defined by the inner cannula, and the other lumen is defined by the annular region between the inner cannula and the tracheal tube.

9. The apparatus of claim 1 wherein the inner cannula extends to a port in the cap of the adaptor configured to allow the patient to freely inhale and exhale in open exchange with the atmosphere via the inner cannula, and wherein the flow of oxygen-containing gas is delivered via the annular region between the inner cannula and the tracheal tube.

10. The apparatus of claim 1 the cap of the adaptor further comprises a port configured for allowing the patient to freely inhale and exhale in open exchange with the atmosphere via the annular region between the inner cannula and the tracheal tube, and the flow of oxygen-containing gas is delivered via the inner cannula.