Fugitive plasticizer balloon surface treatment for enhanced stent securement
First Claim
1. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent mounted over the balloon, whereinthe balloon comprises polymer material having a fugitive plasticizer distributed therein, the polymer material comprises a polymer that forms inter-chain hydrogen bonds and the fugitive plasticizer comprises a polar organic compound.
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0 Petitions
Accused Products
Abstract
In an assembly of a balloon mounted on a catheter and a stent mounted over the deflated balloon, the balloon is provided with a fugitive plasticizer before the stent is crimped over the balloon. The fugitive plasticizer can soften the balloon surface so that molding of the balloon surface to conform to the crimped stent occurs. The fugitive plasticizer is removed before the assembly is used.
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Citations
21 Claims
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1. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent mounted over the balloon, wherein
the balloon comprises polymer material having a fugitive plasticizer distributed therein, the polymer material comprises a polymer that forms inter-chain hydrogen bonds and the fugitive plasticizer comprises a polar organic compound.
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13. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent mounted over the balloon, wherein
the balloon comprises polymer material having a fugitive plasticizer distributed therein and the fugitive plasticizer is a compound or mixture of compounds that can solubilize the polymer only at elevated temperatures above about 120° - C., but functions as a fugitive plasticizer at ambient temperature.
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14. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent mounted over the balloon, wherein
the balloon comprises polymer material having a fugitive plasticizer distributed therein, and wherein the fugitive plasticizer is a member of the group consisting of polyhydric alcohols; - mono- and di-alkyl glycol ethers;
acetate esters of glycol monoalkyl ethers;
isophorone;
benzyl alcohol;
3-methoxybutanol-1;
3-methoxybutanol-3;
ethylene carbonate;
propylene carbonate;
phenylglycol ethers;
2,2,4-trimethyl-1,3-pentanediolmonoisobutyrate;
phenols;
dihydroxybenzenes; and
mixtures of two or more thereof.
- mono- and di-alkyl glycol ethers;
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15. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent with sidewall openings therethrough crimped over the balloon, the stent having a coating comprising a drug, wherein the stent has been crimped on the balloon while the balloon was in a softened state using a fugitive plasticizer to produce a pillowing of the balloon material between sidewall openings in the stent, said pillowing having been produced without exposing the drug coating to a limiting temperature in excess of 50°
- C. or exposing the balloon material to a solvent therefor.
- View Dependent Claims (16, 17, 18)
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19. An assembly comprising a catheter, a deflated balloon mounted on the catheter and a stent with sidewall openings therethrough mounted over the balloon,
wherein the assembly was formed by crimping the stent on the balloon while the balloon was in a softened state to produce a pillowing of the balloon material between sidewall openings in the stent, said softened state having been provided by incorporation of a fugitive plasticizer into the balloon material without substantial swelling thereof, while the balloon was in said softened state the balloon was not pressurized, and said fugitive plasticizer was subsequently substantially removed, leaving an ambient equilibrated amount of fugitive plasticizer remains in the polymer material after extended equilibration at ambient temperature, humidity and pressure.
Specification