Systems and methods to obtain a myocardial mass index indicative of an at-risk myocardial region
First Claim
1. A method for diagnosing a risk of cardiac disease, the method comprising the steps of:
- obtaining an image showing a vasculature of at least part of a patient'"'"'s biological tree;
identifying a luminal cross-sectional area of a side branch vessel from the image;
identifying a luminal cross-sectional area of a main artery most proximal to the side branch vessel from the image;
determining a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the most proximal artery, wherein such region is a percentage of the mass perfused by the most proximal artery and quantitatively calculated using the cross-sectional areas of the side branch and the most proximal main artery;
diagnosing a risk of cardiac disease based on a diameter of the side branch vessel and a size of the myocardial region at risk for infarct perfused by the side branch, wherein a relationship between the size of the myocardial region at risk for infarct and the cross-sectional area of the side branch is substantially linear; and
administering a treatment to the patient if a risk of cardiac disease at or above a predefined acceptable risk level is diagnosed.
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Abstract
Systems and methods to obtain a myocardial mass index indicative of an at-risk myocardial region. In at least one embodiment, a method for diagnosing a risk of cardiac disease is provided, the method comprising the steps of identifying a luminal cross-sectional area of a side branch vessel, identifying a luminal cross-sectional area of a main artery most proximal to the side branch vessel, determining a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the most proximal artery, wherein such region is based on a relationship between the cross-sectional areas of the side branch and the most proximal main artery, and diagnosing a risk of cardiac disease based on a diameter of the side branch and the size of the myocardial region at risk for infarct perfused by the side branch.
21 Citations
20 Claims
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1. A method for diagnosing a risk of cardiac disease, the method comprising the steps of:
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obtaining an image showing a vasculature of at least part of a patient'"'"'s biological tree; identifying a luminal cross-sectional area of a side branch vessel from the image; identifying a luminal cross-sectional area of a main artery most proximal to the side branch vessel from the image; determining a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the most proximal artery, wherein such region is a percentage of the mass perfused by the most proximal artery and quantitatively calculated using the cross-sectional areas of the side branch and the most proximal main artery; diagnosing a risk of cardiac disease based on a diameter of the side branch vessel and a size of the myocardial region at risk for infarct perfused by the side branch, wherein a relationship between the size of the myocardial region at risk for infarct and the cross-sectional area of the side branch is substantially linear; and administering a treatment to the patient if a risk of cardiac disease at or above a predefined acceptable risk level is diagnosed. - View Dependent Claims (2, 3, 4, 5)
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6. A method for diagnosing a risk of cardiac disease, the method comprising the steps of:
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obtaining an image showing a vasculature of at least part of a patient'"'"'s biological tree; identifying a luminal cross-sectional area of a side branch vessel from the image; identifying a luminal cross-sectional area of a left main coronary artery from the image; identifying a luminal cross-sectional area of a right coronary artery from the image; determining a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the entire heart, wherein such region is a percentage of the mass perfused by the entire heart and quantitatively calculated using the cross-sectional areas of the side branch, left main coronary artery and a right coronary artery; diagnosing a risk of cardiac disease based on a diameter of the side branch and a size of the myocardial region at risk for infarct perfused by the side branch, wherein a relationship between the size of the myocardial region at risk for infarct and the cross-sectional area of the side branch is substantially linear; and administering a treatment to the patient if a risk of cardiac disease at or above a predefined acceptable risk level is diagnosed. - View Dependent Claims (7, 8, 9)
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10. A system for diagnosing a risk of cardiac disease, the system comprising:
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a processor; a storage medium operably connected to the processor, the storage medium capable of receiving and storing data relative of measurements from a vasculature of a vessel; wherein the processor is operable to; produce an image showing a vasculature of at least part of a patient'"'"'s biological tree, the image to be received and stored in the storage medium; identify a luminal cross-sectional area of a side branch vessel from the image; identify a luminal cross-sectional area of a main artery most proximal to the side branch vessel from the image; determine a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the most proximal artery, wherein such region is a percentage of the mass perfused by the most proximal artery and quantitatively calculated using the cross-sectional areas of the side branch and the most proximal main artery, wherein a relationship between the size of the myocardial region at risk for infarct and the cross-sectional area of the side branch is substantially linear; and diagnose a risk of cardiac disease based on a diameter of the side branch and a size of the myocardial region at risk for infarct perfused by the side branch. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. A system for diagnosing a risk of cardiac disease, the system comprising:
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a processor; a storage medium operably connected to the processor, the storage medium capable of receiving and storing data relative of measurements from a vasculature of a vessel; wherein the processor is operable to; produce an image showing a vasculature of at least part of a patient'"'"'s biological tree, the image to be received and stored in the storage medium; identify a lumen area of a side branch vessel from the image; identify a cross sectional area of a left main coronary artery from the image; identify a cross sectional area of a right coronary artery from the image; determine a myocardial region at risk for infarct from side branch occlusion relative to a mass perfused by the entire heart, wherein such region is a percentage of the mass perfused by the entire heart and quantitatively calculated using the cross-sectional areas of the side branch, left main coronary artery, and right coronary artery, wherein a relationship between the size of the myocardial region at risk for infarct and the cross-sectional area of the side branch is substantially linear; and diagnose a risk of cardiac disease based on a diameter of the side branch and a size of the myocardial region at risk for infarct perfused by the side branch. - View Dependent Claims (18, 19, 20)
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Specification