Delivery of two or more medicaments through a single dose selection and dispense interface
First Claim
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1. A drug delivery system operable to deliver a first medicament and a second medicament through a single dispense interface, comprising:
- a primary drug delivery device comprising;
a primary reservoir containing the first medicament, wherein the first medicament comprises at least one first drug agent, and wherein the primary reservoir comprises a pierceable seal, anda dose button operably connected to the primary reservoir; and
a medicated module configured to be attached to a distal end of the primary drug delivery device, the medicated module comprising;
an engagement interface configured such that attachment of the medicated module to the distal end of the primary drug delivery device causes the engagement interface to pierce the pierceable seal of the primary reservoir,a dispense interface configured for fluid communication with the primary reservoir via the engagement interface, anda secondary reservoir containing the second medicament, wherein the second medicament comprises at least one second drug agent, and wherein the secondary reservoir is configured for fluid communication with the dispense interface,wherein the medicated module is configured such that when the medicated module is attached to the distal end of the primary drug delivery device, a single activation of the dose button causes the first medicament from the primary reservoir and a non-user settable dose of the second medicament to be expelled through the dispense interface, andwhere the single activation of the dose button causes the first medicament from the primary reservoir to be expelled through the dispense interface after a therapeutic dose of the non-user settable dose of second medicament has been expelled through the dispense interface.
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Abstract
An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
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Citations
15 Claims
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1. A drug delivery system operable to deliver a first medicament and a second medicament through a single dispense interface, comprising:
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a primary drug delivery device comprising; a primary reservoir containing the first medicament, wherein the first medicament comprises at least one first drug agent, and wherein the primary reservoir comprises a pierceable seal, and a dose button operably connected to the primary reservoir; and a medicated module configured to be attached to a distal end of the primary drug delivery device, the medicated module comprising; an engagement interface configured such that attachment of the medicated module to the distal end of the primary drug delivery device causes the engagement interface to pierce the pierceable seal of the primary reservoir, a dispense interface configured for fluid communication with the primary reservoir via the engagement interface, and a secondary reservoir containing the second medicament, wherein the second medicament comprises at least one second drug agent, and wherein the secondary reservoir is configured for fluid communication with the dispense interface, wherein the medicated module is configured such that when the medicated module is attached to the distal end of the primary drug delivery device, a single activation of the dose button causes the first medicament from the primary reservoir and a non-user settable dose of the second medicament to be expelled through the dispense interface, and where the single activation of the dose button causes the first medicament from the primary reservoir to be expelled through the dispense interface after a therapeutic dose of the non-user settable dose of second medicament has been expelled through the dispense interface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 15)
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11. A method of dispensing a first medicament and a second medicament from separate reservoirs, comprising, in combination, the steps of:
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providing a primary drug delivery device comprising; a primary reservoir containing the first medicament, wherein the first medicament comprises at least one first drug agent, and a dose button operably connected to the primary reservoir; providing a medicated module configured to be attached to a distal end of the primary drug delivery device, the medicated module comprising; a dispense interface configured for fluid communication with the primary reservoir, and a secondary reservoir containing the second medicament, wherein the second medicament comprises at least one second drug agent, and wherein the secondary reservoir is configured for fluid communication with the dispense interface; attaching the medicated module to the distal end of the primary drug delivery device; activating the dose button, wherein activation of the dose button causes the first medicament from the primary reservoir and a non-user settable dose of the second medicament from the secondary reservoir to be expelled through the dispense interface, and where the activation of the dose button causes the first medicament from the primary reservoir to be expelled through the dispense interface after a therapeutic dose of the non-user settable dose of second medicament has been expelled through the dispense interface.
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12. A method of dispensing a non-user settable dose of a second medicament and a dose of a first medicament from separate reservoirs, comprising, in combination, the steps of:
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a) setting a dose of the first medicament contained in a primary reservoir using a single dose setter of a primary drug delivery device, the primary reservoir comprising a pierceable seal; b) attaching a medicated module to a distal end of the primary drug delivery device, wherein attachment causes a dispense interface to pierce the pierceable seal of the primary reservoir, and wherein the medicated module comprises a secondary reservoir containing the second medicament; c) moving the set dose of the first medicament from the primary reservoir causing it to flow in a distal direction; and d) expelling the set dose of the first medicament through the dispense interface of the medicated module after expulsion of a therapeutic dose of a non-user settable dose of the second medicament through the dispense interface of the medicated module. - View Dependent Claims (13, 14)
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Specification