UV blocker loaded contact lenses
First Claim
1. A UV absorbing nanoparticle, comprising at least one UV absorbing compound dispersed in a cross-linked gel, wherein the cross-link density is sufficiently high to inhibit diffusion of the UV absorbing compound within the cross-linked gel, wherein the UV absorbing compounds are selected from reacted and unreacted 1,3-diphenyl-1,3-propanedione (DP) and reacted and unreacted 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate (BHPEA), and wherein the nanoparticles are less than 350 nm in diameter.
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Accused Products
Abstract
UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent.
64 Citations
31 Claims
- 1. A UV absorbing nanoparticle, comprising at least one UV absorbing compound dispersed in a cross-linked gel, wherein the cross-link density is sufficiently high to inhibit diffusion of the UV absorbing compound within the cross-linked gel, wherein the UV absorbing compounds are selected from reacted and unreacted 1,3-diphenyl-1,3-propanedione (DP) and reacted and unreacted 2-(4-Benzoyl-3-hydroxyphenoxy)ethyl acrylate (BHPEA), and wherein the nanoparticles are less than 350 nm in diameter.
- 16. A UV absorbing nanoparticle, comprising at least one UV absorbing compound dispersed in a cross-linked gel, wherein the cross-link density is sufficiently high to inhibit diffusion of the UV absorbing compound within the cross-linked gel, and wherein the nanoparticles are less than 350 nm in diameter, wherein the cross-linked gel is the polymerization product of an alkene comprising monomer mixture wherein the average monomer has a plurality of alkene units, and wherein the alkene comprising monomer is propoxylated glyceryl triacrylate (PGT).
Specification