Filamentary devices for treatment of vascular defects

• US 9,597,087 B2
• Filed: 05/01/2009
• Issued: 03/21/2017
• Est. Priority Date: 05/02/2008
• Status: Active Grant

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Sequent Medical, Inc. (Terumo Corporation)
• Inventors: Marchand, Philippe, Cox, Brian J., Rosenbluth, Robert F.
• Primary Examiner(s): WEISBERG, AMY REGINA
• Application Number:
  US12/434,465
• Publication Number:
  US 20090275974A1
• Time in Patent Office: 2,881 Days
• Field of Search: 606/157, 606/200
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104

Abstract

Devices and methods for treatment of a patient'"'"'s vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell configured to occlude blood flow therethrough.

Claims

1. A device for treatment of a cerebral aneurysm, comprising:

a self-expanding resilient permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, the number of filaments being between 125 and 180, the plurality of elongate filaments including filaments of at least two different transverse dimensions, wherein the plurality of filaments ate secured at the proximal and distal ends thereof,

wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter with each filament in the plurality of filaments extending longitudinally between the proximal and distal ends and forming a substantially cylindrical configuration, and

wherein the permeable shell has an expanded relaxed state with a globular, axially shortened configuration relative to the radially constrained state, each filament forming a smooth arc between the proximal and distal ends, the permeable shell having a plurality of openings formed between the braided filaments.

2. The device of claim 1, wherein the plurality of elongate filaments comprises a first subset of filaments having a transverse dimension of about 0.04 mm to about 0.1 mm.

3. The device of claim 1, wherein the plurality of elongate filaments comprises a second subset of filaments having a transverse dimension of about 0.015 mm to about 0.05 mm.

4. The device of claim 1, wherein the openings formed between the braided filaments in a defect spanning portion of the permeable shell are about 0.005 inches to about 0.04 inches.

5. The device of claim 1, wherein a transverse dimension of the permeable shell in the expanded relaxed state is about 4 mm to about 30 mm.

6. The device of claim 1, wherein a transverse dimension of the permeable shell in the radially constrained elongated state is about 0.2 mm to about 2 mm.

7. The device of claim 1, wherein a major transverse dimension of the permeable shell in the expanded relaxed state is about 10 times to about 20 times the transverse dimension of the permeable shell in a radially constrained elongated state.

8. The device of claim 1, further comprising a detachment mechanism at the proximal end.

9. The device of claim 1, wherein each of the filaments of the plurality of filaments comprise a superelastic material.

10. The device of claim 9, wherein the superelastic material is a shape memory metal.

11. The device of claim 10, wherein the shape memory metal comprises a NiTi allow.

12. The device of claim 1, wherein at least some of the filaments in the plurality of filaments are secured to adjacent filaments at a point of contact therebetween.

13. The device of claim 12, wherein the adjacent filaments are secured to each other by adhesive bonding.

14. The device of claim 12, wherein adjacent filaments are secured to each other by adhesive welding.