Methods and systems for treatment of tissue in a body lumen

• US 9,597,147 B2
• Filed: 04/21/2015
• Issued: 03/21/2017
• Est. Priority Date: 11/16/1999
• Status: Expired due to Fees

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Jackson, Jerome, Stern, Roger A.
• Primary Examiner(s): HUPCZEY, JR, RONALD JAMES
• Application Number:
  US14/691,640
• Publication Number:
  US 20150297293A1
• Time in Patent Office: 700 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00482 Digestive system
• CPC Class Codes: A61B 2018/00488 Esophagus
• CPC Class Codes: A61B 2018/00494 Stomach, intestines or bowel
• CPC Class Codes: A61B 2018/00553 Sphincter
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00738 Depth, e.g. depth of ablation
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/126 bipolar
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 5/037 Measuring oesophageal pressure
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/1076 for measuring dimensions inside body cavities, e.g. using catheters A61B3/1005 takes precedence
• CPC Class Codes: A61B 5/4233 : oesophagus
• CPC Class Codes: A61B 5/6885 : Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61N 1/06 : for high-frequency therapy
• CPC Class Codes: A61N 1/403 : for thermotherapy, e.g. hyperthermia

Abstract

A system for measuring physiologic characteristics or treating tissue in a body lumen. The system may be used for treating abnormal mucosa in the esophagus. The system comprises an energy delivery device, such as an ablation device including an electrode support and an electrode pattern on the support. The ablation device may expand in size from a pre-deployed state to a deployed state. The system may include a sizing device having an inflatable balloon on a distal end of a catheter that is inflated with an expansion medium to expand the balloon to engage the wall of the esophagus so that the internal cross-section can be calculated or measured. The sizing device may also a controller for delivering an expansion medium and measuring the amount and pressure of the expansion medium inside the catheter. Methods of treating or diagnosing tissue are also disclosed.

Claims

1. A system for treating abnormal tissue at a treatment location within a body lumen comprising:

an electrode support comprising a flexible, non-distensible backing with a pre-deployed state and a deployed state, wherein a circumference of the electrode support in the deployed state adapts to engage an inner wall of the body lumen;

an inflatable member around which the electrode support is wrapped such that the electrode support extends continuously around a circumference of the inflatable member and continuously covers the circumference along a length of the inflatable member between a distal end and a proximal end of the inflatable member; and

an electrode pattern positioned on the electrode support and extending around the circumference of the electrode support in the deployed state.

2. The system of claim 1, wherein the electrode support at least partially overlaps itself in the pre-deployed state.

3. The system of claim 1, wherein the electrode support furls and unfurls from around the inflatable member as the electrode support transitions between the pre-deployed and deployed states.

4. The system of claim 1, further comprising an elastic member coupled with the electrode support configured to bias the electrode support in a furled configuration.

5. The system of claim 1, wherein the electrode pattern comprises a plurality of longitudinal electrode zones.

6. The system of claim 5, wherein the plurality of longitudinal electrode zones are all equal in width.

7. The system of claim 5, wherein the plurality of longitudinal electrode zones comprise at least two longitudinal electrode zones with different widths.

8. The system of claim 1, wherein the electrode pattern comprises a plurality of selectively activated electrode zones.

9. The system of claim 1, wherein the electrode pattern comprises a plurality of longitudinal electrode zones, the plurality of longitudinal electrode zones configured to be sequentially activated beginning with a first longitudinal electrode zone adjacent to a free end of the electrode support.

10. The system of claim 1, wherein the inflatable member comprises a cylindrical balloon.

11. A device for treating abnormal tissue at a treatment location within a body lumen comprising:

an electrode support comprising a flexible, non-distensible backing with a pre-deployed state and a deployed state, wherein a circumference of the electrode support in the deployed state adapts to engage an inner wall of the body lumen; and

an inflatable member around which the electrode support is wrapped such that the electrode support extends continuously around a circumference of the inflatable member and continuously covers the circumference along a length of the inflatable member between a distal end and a proximal end of the inflatable member; and

an electrode pattern positioned on the electrode support and configured to selectively deliver energy to axial portions of the engaged wall of the body lumen.

12. The system of claim 11, wherein the electrode support at least partially overlaps itself in the pre-deployed state.

13. The system of claim 11, wherein a first end of the electrode support is adhered to the inflatable member, and a free end opposite the first end at least partially overlaps the first end when the electrode support is in the pre-deployed state.

14. The system of claim 11, wherein the electrode support furls and unfurls from around the inflatable member as the inflatable member is inflated and deflated.

15. The system of claim 11, further comprising an elastic member coupled with the electrode support configured to bias the electrode support in the pre-deployed state.

16. The system of claim 11, wherein the electrode pattern comprises a plurality of longitudinal electrode zones.

17. The system of claim 16, wherein the plurality of longitudinal electrode zones are all equal in width.

18. The system of claim 11, wherein the electrode pattern comprises a plurality of selectively activated electrode zones.

19. The system of claim 18, wherein the plurality of selectively activated electrode zones are configured to be sequentially activated beginning with a first longitudinal electrode zone adjacent to a free end of the electrode support.

20. The system of claim 11, wherein the electrode pattern comprises at least a bipolar electrode array.