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Nanoparticles for treatment of allergy

  • US 9,597,385 B2
  • Filed: 04/23/2013
  • Issued: 03/21/2017
  • Est. Priority Date: 04/23/2012
  • Status: Active Grant
First Claim
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1. A method of treating allergy, the method comprising:

  • administering a pharmaceutical composition to a subject suffering from or susceptible to allergic reaction to a particular allergen, such that at least one of the subject'"'"'s symptoms of allergy are reduced or delayed, wherein;

    (i) the pharmaceutical composition comprises a population of nanoparticles formed from at least one polymer, which nanoparticles comprise at least one microbial mimic entity,wherein the at least one microbial mimic entity is a pathogen-associated molecular pattern (PAMP);

    (ii) the pharmaceutical composition is substantially free of the particular allergen; and

    (iii) the pharmaceutical composition is formulated for delivery to the subject, andwherein the administering does not also comprise administering the particular allergen.

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