Intraluminal devices and systems

• US 9,597,480 B2
• Filed: 10/06/2015
• Issued: 03/21/2017
• Est. Priority Date: 10/07/2009
• Status: Active Grant

• Current Assignee: Endophys Holding LLC
• Original Assignee: Endophys Holding LLC
• Inventors: Purdy, Phillip D., Ferry, Steven J.
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): SHAH, NILAY J
• Application Number:
  US14/876,764
• Publication Number:
  US 20160022956A1
• Time in Patent Office: 532 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 2562/12 Manufacturing methods specially adapted for producing sensors for in-vivo measurements
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/02154 by optical transmission
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61M 2025/0001 for pressure measurement
• CPC Class Codes: A61M 2025/0002 with a pressure sensor at the distal end
• CPC Class Codes: A61M 2025/0003 having an additional lumen transmitting fluid pressure to the outside for measurement
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 25/0012 with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
• CPC Class Codes: A61M 25/005 with embedded materials for reinforcement, e.g. wires, coils, braids
• CPC Class Codes: A61M 25/0097 characterised by the hub connectors A61M39/10
• CPC Class Codes: Y10T 29/49002 Electrical device making

Abstract

Medical devices, perfusion systems, and methods for detecting a pressure within a space in a subject and for perfusion of fluid into a space in a subject. The space may be a fluid-filled space, or a space that is depleted of fluid due to an obstruction to fluid flow into the space. Methods for forming the medical devices.

Claims

1. An intravascular system comprising:

a sheath comprising a primary sheath lumen and a sensor sheath lumen, the sheath having a sheath length, wherein the sensor sheath lumen terminates at an opening along a distal end of the sheath, the opening located along an exterior of the sheath; and

a hub configured to couple to a proximal end of the sheath, wherein the hub comprises;

a primary hub lumen configured to be placed in fluid communication with the primary sheath lumen when the hub is coupled to the sheath;

a sensor hub lumen terminating at a sensor port and configured to be placed in fluid communication with the sensor sheath lumen when the hub is coupled to the sheath; and

a flushing lumen terminating at a flushing port and in fluid communication with the primary hub lumen;

wherein a transmission line is configured to be positioned within the sensor sheath lumen and the sensor hub lumen;

wherein the transmission line is configured to couple to a sensor positioned within the sensor sheath lumen at or adjacent the opening of the sensor sheath lumen along the distal end of the sheath, wherein the sensor is configured to detect a parameter of fluid passing into the opening from a space within a subject;

wherein the primary sheath lumen is separate from the sensor sheath lumen, such that the primary sheath lumen is not in direct fluid communication with the sensor sheath lumen and does not impinge on the sensor sheath lumen along the sheath length; and

wherein the primary hub lumen is separate from the sensor hub lumen, such that the primary hub lumen is not in direct fluid communication with the sensor hub lumen.

2. The system of claim 1, wherein the sensor comprises a pressure sensor.

3. The system of claim 1, wherein the transmission line is secured to an interior of the sensor sheath lumen using an embedding medium.

4. The system of claim 1, wherein the sensor comprises a fiber-optic sensor.

5. The system of claim 1, wherein the primary hub lumen is aligned with the sheath primary lumen when the hub is coupled to the sheath.

6. The system of claim 1, wherein the sensor hub lumen is angled relative to the sensor sheath lumen when the hub is coupled to the sheath.

7. The system of claim 1, further comprising a flushing flow control device in fluid communication with the flushing lumen of the hub, wherein the flushing flow control device is configured to regulate a passage of flushing fluid through the flushing lumen and into the primary hub lumen.

8. The system of claim 1, further comprising a primary hub flow control device, wherein the primary hub lumen is configured to be placed in fluid communication with the primary hub flow control device, the primary hub flow control device being configured to seal the primary hub lumen and the primary sheath lumen from an outside environment.

9. The system of claim 8, wherein the primary hub flow control device comprises a valve.

10. The system of claim 8, wherein the primary hub flow control device comprises a self-sealing member.

11. The system of claim 8, wherein the primary hub flow control device is positioned along a proximal end of the hub.

12. The system of claim 8, wherein the primary hub flow control device is positioned at least partially within the primary hub lumen.

13. The system of claim 1, wherein the sheath and the hub form a unitary structure.

14. An intravascular system comprising:

a sheath comprising a primary sheath lumen and a sensor sheath lumen, wherein the sensor sheath lumen terminates at an opening along a distal end of the sheath, the opening being located along an exterior of the sheath;

wherein the sensor sheath lumen is not in direct fluid communication with the primary sheath lumen and does not impinge on the primary sheath lumen.

a hub configured to couple to a proximal end of the sheath, wherein the hub comprises;

a primary hub lumen;

a sensor hub lumen; and

a flushing lumen in fluid communication with the primary hub lumen;

wherein the hub is configured to be coupled to the sheath;

wherein the primary hub lumen is configured to be placed in fluid communication with the primary sheath lumen of the sheath when the hub is coupled to the sheath;

wherein the sensor hub lumen is configured to be placed in fluid communication with the sensor sheath lumen when the hub is coupled to the sheath;

wherein a transmission line is configured to be positioned within the sensor sheath lumen and the sensor hub lumen;

wherein the transmission line is configured to couple to a sensor, the sensor being positioned within the sensor sheath lumen at or adjacent the opening of the sensor sheath lumen; and

wherein the sensor is configured to detect a parameter of fluid passing into the opening from a space within a subject.

15. The system of claim 14, wherein the sensor comprises a pressure sensor.

16. The system of claim 14, wherein the transmission line is secured to an interior of the sensor sheath lumen using an embedding medium.

17. The system of claim 14, further comprising a primary hub flow control device, wherein the primary hub lumen is configured to be placed in fluid communication with the primary hub flow control device, the primary hub flow control device being configured to seal the primary hub lumen from an outside environment.

18. The system of claim 14, wherein the sensor comprises a fiber-optic sensor.

19. The system of claim 14, wherein the sheath and the hub form a unitary structure.