Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates
First Claim
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1. A process for the preparation of a 4-amino-3-chloro-5-fluoro-6-(substituted)picolinate of the Formula I
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Abstract
4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, reaction with hydrazine, halogenation, hydrolysis and esterification, and transition metal assisted coupling.
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3 Claims
- 1. A process for the preparation of a 4-amino-3-chloro-5-fluoro-6-(substituted)picolinate of the Formula I
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3. An improved process of increasing the amount of recoverable 3-chloro-4,5,6-trifluoropicolinonitrile (Formula B)
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