Autonomous, ambulatory analyte monitor or drug delivery device
First Claim
1. An analyte monitoring device operable to draw a fluid sample from a subject, the device comprising:
- a plurality of microneedles disposed radially outward on a circular carrier, the circular carrier rotatably connected to the device, wherein each of the plurality of microneedles comprises a longitudinal axis and is individually actuatable;
a plurality of microchannels, wherein each of the plurality of microneedles is at least intermittently in fluid communication with a corresponding microchannel, wherein each of the plurality of microneedles is connected to and moveable with a corresponding fluidic capture site and is configured to collect the fluid sample from the subject, wherein the corresponding fluidic capture site is configured to fluidly couple to and deliver the fluid sample to at least one of the plurality of microchannels, and wherein the plurality of microchannels are on a surface that is transverse to the longitudinal axis of at least one of the plurality of microneedles;
at least one actuator operable to drive each microneedle and corresponding fluidic capture site in a non-rectilinear path relative to the circular carrier to collect the fluid sample from the subject and to deliver the fluid sample to the at least one of the plurality of microchannels; and
a controller operable to initiate analyte testing of the fluid sample.
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Accused Products
Abstract
The invention relates to analyte monitoring/drug delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The invention can optionally provide for calibration without intervention of the user and can also provide for semi-continuous monitoring for day and night time. The invention can provide up to four, or more, weeks of operation. The invention can provide for a device that is relatively small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents.
223 Citations
22 Claims
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1. An analyte monitoring device operable to draw a fluid sample from a subject, the device comprising:
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a plurality of microneedles disposed radially outward on a circular carrier, the circular carrier rotatably connected to the device, wherein each of the plurality of microneedles comprises a longitudinal axis and is individually actuatable; a plurality of microchannels, wherein each of the plurality of microneedles is at least intermittently in fluid communication with a corresponding microchannel, wherein each of the plurality of microneedles is connected to and moveable with a corresponding fluidic capture site and is configured to collect the fluid sample from the subject, wherein the corresponding fluidic capture site is configured to fluidly couple to and deliver the fluid sample to at least one of the plurality of microchannels, and wherein the plurality of microchannels are on a surface that is transverse to the longitudinal axis of at least one of the plurality of microneedles; at least one actuator operable to drive each microneedle and corresponding fluidic capture site in a non-rectilinear path relative to the circular carrier to collect the fluid sample from the subject and to deliver the fluid sample to the at least one of the plurality of microchannels; and a controller operable to initiate analyte testing of the fluid sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification