Detection of valid signals versus artifacts in a multichannel mapping system

• US 9,610,045 B2
• Filed: 07/31/2015
• Issued: 04/04/2017
• Est. Priority Date: 07/31/2015
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Du, Juan, Ghosh, Subham
• Primary Examiner(s): Gedeon, Brian T
• Assistant Examiner(s): Tejani, Ankit D
• Application Number:
  US14/815,537
• Publication Number:
  US 20170027524A1
• Time in Patent Office: 613 Days
• Field of Search: None
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/339 Displays specially adapted therefor
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control

Abstract

A system and associated method is disclosed for determining whether signal is valid. The system comprises an electrode apparatus comprising a plurality of electrodes configured to be located proximate tissue of a patient. A display apparatus comprising a graphical user interface, wherein the graphical user interface is configured to present information to a user. A computing apparatus coupled to the electrode apparatus and display apparatus, wherein the computing apparatus is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid and sufficiently strong by i) calculating a first derivative of the signal; ii) determining a minimum and maximum derivative from the first derivative; iii) determining whether signs of the minimum and maximum derivative are different; and in response to determining whether the signs of the minimum and maximum derivative are different, displaying on a display apparatus whether the signal is valid.

Claims

1. A system for use in monitoring cardiac signals comprising:

an electrode apparatus comprising a plurality of electrodes configured to be located proximate tissue of a patient;

display apparatus comprising a graphical user interface, wherein the graphical user interface is configured to present information to a user;

computing apparatus coupled to the electrode apparatus and display apparatus, wherein the computing apparatus is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid and sufficiently strong by;

i) calculating a first derivative of the signal;

ii) determining a minimum and maximum of the first derivative;

iii) determining whether signs of the minimum and maximum of the first derivative are different; and

in response to determining whether the signs of the minimum and maximum of the first derivative are different, displaying on the graphical user interface whether the signal is valid.

2. The system of claim 1, wherein the signal is declared valid when the signs of the minimum and maximum of the first derivative are the same.

3. The system of claim 1 further comprising:

calculating a ratio of an absolute value of a larger first derivative value to an absolute value of a smaller first derivative value.

4. The system of claim 3 further comprising:

determining whether the ratio is greater than a pre-selected number;

and in response to determining whether the ratio is greater than a pre-selected number, determining whether the signal is valid.

5. The system of any of claim 4 wherein in response to determining the signs of the minimum and maximum of the first derivative are different, declaring the signal is valid.

6. The system of any of claim 5 wherein in response to determining the signs of the minimum and maximum of the first derivative are the same, declaring the signal is invalid.

7. The method of claim 1, further comprising:

eliminating any channel or electrode for use in a multichannel system in which an invalid signal is acquired.

8. A method for determining whether a signal is valid or an artifact in a multichannel mapping system, the multichannel mapping system comprising a processor connected to an electrode apparatus and a display apparatus, the electrode apparatus located proximate tissue of a patient, wherein the processor is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid, the method comprising:

acquiring a signal from an electrode associated with an electrode apparatus allows the processor, executing a set of instructions, to perform a set of actions comprising;

i) calculating a first derivative of the signal;

ii) determining a minimum and maximum from the first derivative;

iii) determining whether signs of the minimum and maximum are different; and

in response to determining whether signs of the minimum and maximum are different, displaying on the display apparatus whether the signal is valid.

9. The method of claim 8, wherein the signal is declared valid in response to determining the signs of the minimum and maximum are the same.

10. The method of claim 8, wherein the signal is declared invalid in response to determining the signs of the minimum and maximum are different.

11. The method of claim 10, wherein the invalid signal is determined to be an artifact.

12. The method of claim 11 further comprising:

determining whether the ratio is greater than a pre-selected number; and

in response to determining whether the ratio is greater than a pre-selected number, determining whether the signal is valid.

13. The method of claim 8 further comprising:

calculating a ratio of an absolute value of a larger derivative value to an absolute value of a smaller derivative value.

14. The method of claim 8 wherein determining the signal is valid if the signs of the minimum and maximum are different.

15. The method of claim 8 wherein determining the signal is invalid in response to determining signs of the minimum and maximum are the same.

16. The method of claim 8 wherein the system uses an electrode apparatus located around a patient'"'"'s torso.

17. The method of claim 8 wherein the system is used during ablation of human tissue.

18. The method of claim 8 wherein the system is applied to a patient diagnosed with atrial fibrillation.

19. The method of claim 8 wherein the system is used during cardiac pacing.

20. The method of claim 8 wherein the system is used during cardiac rhythm therapy.

21. The method of claim 8 wherein the system is used to locate optimal electrode placement for cardiac therapy.

22. The method of claim 8 wherein the system is used to locate optimal electrode placement for cardiac therapy.

23. A system for use in monitoring cardiac signals comprising:

an electrode apparatus comprising a plurality of electrodes configured to be located proximate tissue of a patient;

display apparatus comprising a graphical user interface, wherein the graphical user interface is configured to present information to a user;

computing apparatus coupled to the electrode apparatus and display apparatus, wherein the computing apparatus is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid and sufficiently strong by;

i) calculating a first derivative of the signal;

ii) determining a minimum and maximum of the first derivative;

iii) determining whether signs of the minimum and maximum of the first derivative are different, and if the signs are different, declaring the signal to be invalid;

otherwise, if the signs are the same, calculating a ratio of an absolute value of a larger first derivative value to an absolute value of a smaller first derivative value;

iv) determining whether the ratio is greater than a pre-selected number; and

in response to determining whether the ratio is greater than the pre-selected number, determining whether the signal is valid.

24. A system for determining whether a signal is valid or an artifact in a mapping system comprising a processor connected to an electrode and a display apparatus, the electrode located proximate tissue of a patient, wherein the processor is configured to determine whether a signal acquired from a channel associated with the electrode is valid, the system comprising:

means for acquiring a signal from the electrode allows the processor, executing a set of instructions, to perform a set of actions comprising;

i) calculating a first derivative of the signal;

ii) determining a minimum and maximum from the first derivative;

iii) determining whether signs of the minimum and maximum are different; and

in response to determining whether signs of the minimum and maximum are different, displaying on the display apparatus whether the signal is valid.

25. A non-transitory machine readable medium containing executable computer program instructions which when executed by a data processing system cause said system to perform a method of displaying cardiac signals, the method comprising:

acquiring a signal from an electrode associated with an electrode apparatus allows the processor, executing a set of instructions, to perform a set of actions comprising;

i) calculating a first derivative of the signal;

ii) determining a minimum and maximum from the first derivative;

iii) determining whether signs of the minimum and maximum are different; and

in response to determining whether signs of the minimum and maximum are different, displaying on the display apparatus whether the signal is valid.