Method and apparatus for fractional flow reserve measurements
First Claim
1. A method of determining fractional flow reserve (FFR) in a blood vessel having a stenosis, the method comprising:
- injecting a fluid with a fluid delivery system into the blood vessel upstream of the stenosis using a power fluid injector;
measuring a pressure drop across the stenosis with the fluid delivery system during injection of the fluid with the power fluid injector;
reducing or discontinuing injecting the fluid when retrograde flow is present in the blood vessel; and
calculating FFR from the measured pressure drop.
1 Assignment
0 Petitions
Accused Products
Abstract
A method of determining fractional flow reserve (FFR) in a blood vessel having stenosis includes injecting fluid into the blood vessel upstream of the stenosis using a power fluid injector, measuring pressure drop across the stenosis, and calculating FFR from measured pressure drop. The injected fluid may comprise a contrast medium. Further action may include placing a pressure sensor proximal of the stenosis, injecting fluid into the blood vessel upstream of the stenosis using the power fluid injector, and measuring pressure in the blood vessel proximal of the stenosis. The pressure sensor may then be repositioned to a position distal of the stenosis, fluid may be reinjected into the blood vessel upstream of the stenosis using the power fluid injector, and pressure may be measured in the blood vessel distal of the stenosis.
97 Citations
26 Claims
-
1. A method of determining fractional flow reserve (FFR) in a blood vessel having a stenosis, the method comprising:
-
injecting a fluid with a fluid delivery system into the blood vessel upstream of the stenosis using a power fluid injector; measuring a pressure drop across the stenosis with the fluid delivery system during injection of the fluid with the power fluid injector; reducing or discontinuing injecting the fluid when retrograde flow is present in the blood vessel; and calculating FFR from the measured pressure drop. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
-
-
15. A method of determining fractional flow reserve (FFR) in a blood vessel having a stenosis, the method comprising:
-
inserting a multi-lumen catheter into the blood vessel; injecting a fluid with a fluid delivery system into the blood vessel upstream of the stenosis using a power fluid injector; measuring a pressure drop across the stenosis with the fluid delivery system during injection of the fluid with the power fluid injector; reducing or discontinuing injecting the fluid when retrograde flow is present in the blood vessel; and calculating FFR from the measured pressure drop. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
-
Specification