Self-expanding interposed member spacing protective sleeve from restenosis restraining agent coated balloon catheter
First Claim
Patent Images
1. A treatment device comprising:
- a device body having a shaft;
an inflatable balloon disposed at a distal portion of the shaft, the inflatable balloon possessing an outer surface;
a biologically active agent on the outer surface of the inflatable balloon and containing at least one biologically active agent;
a protective sleeve covering the biologically active agent and displaceable proximally in relation to the device body;
an interposed member having a self-expanding function and disposed between the inflatable balloon and the protective sleeve in surrounding relation to the inflatable balloon, the entirety of the interposed member disposed between the inflatable balloon and the protective sleeve having the self-expanding function, and the interposed member is displaceable proximally in relation to the device body to be completely retracted from the inflatable balloon, so that when the inflatable balloon expands the biologically active agent on the outer surface of the inflatable balloon directly contacts a target site and the inflatable balloon does not contact the interposed member; and
the interposed member expanding, while still surrounding the inflatable balloon, when the protective sleeve is displaced proximally.
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Accused Products
Abstract
A treatment device includes: a balloon; a biologically active agent part applied on an outer surface of the balloon; a protective sleeve encircling the balloon and being displaceable proximally; and an interposed member having a self-expanding function arranged between the balloon and the protective sleeve. When the protective sleeve is moved proximally in order for the balloon to be exposed to the inside of a blood vessel, the presence of the interposed member prevents the biologically active agent part from being scraped and peeled off by the inner surface of the protective sleeve.
69 Citations
19 Claims
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1. A treatment device comprising:
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a device body having a shaft; an inflatable balloon disposed at a distal portion of the shaft, the inflatable balloon possessing an outer surface; a biologically active agent on the outer surface of the inflatable balloon and containing at least one biologically active agent; a protective sleeve covering the biologically active agent and displaceable proximally in relation to the device body; an interposed member having a self-expanding function and disposed between the inflatable balloon and the protective sleeve in surrounding relation to the inflatable balloon, the entirety of the interposed member disposed between the inflatable balloon and the protective sleeve having the self-expanding function, and the interposed member is displaceable proximally in relation to the device body to be completely retracted from the inflatable balloon, so that when the inflatable balloon expands the biologically active agent on the outer surface of the inflatable balloon directly contacts a target site and the inflatable balloon does not contact the interposed member; and the interposed member expanding, while still surrounding the inflatable balloon, when the protective sleeve is displaced proximally. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A treatment device positionable in a blood vessel of a living body to treat a stenosed region, the treatment device comprising:
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an elongated shaft possessing a distal portion; an inflatable balloon fixed to the distal portion of the elongated shaft so that the inflatable balloon and the elongated shaft move together, the inflatable balloon possessing an outer surface and an interior; a flow path inside the elongated shaft that communicates with the interior of the inflatable balloon and through which fluid is introduced into the interior of the inflatable balloon to inflate and outwardly expand the inflatable balloon; a restenosis-restraining biologically active agent on the outer surface of the inflatable balloon that restrains restenosis, the restenosis-restraining biologically active agent being applied to the stenosed region of the blood vessel when the inflatable balloon is inflated and outwardly expanded into contact with the stenosed region; a protective sleeve covering an entirety of the outer surface of the inflatable balloon having the restenosis-restraining biologically active agent, the protective sleeve possessing an inner surface and being axially movable in a proximal direction relative to the elongated shaft; a cylindrically shaped interposed member positioned radially between the protective sleeve and the restenosis-restraining biologically active agent to space the protective sleeve from the restenosis-restraining biologically active agent and prevent the restenosis-restraining biologically active agent from contacting the protective sleeve both before the treatment device is delivered to the stenosed region and when the treatment device is at the stenosed region, the entirety of the cylindrically shaped interposed member that is positioned radially between the protective sleeve and the restenosis-restraining biologically active agent possessing a self-expanding function in which the cylindrically shaped interposed member expands radially outwardly when the protective sleeve is axially moved in the proximal direction relative to the cylindrically shaped interposed member, and the cylindrically shaped interposed member is configured to be completely retracted from the inflatable balloon to allow the restenosis-restraining biologically active agent on the outer surface of the inflatable balloon to directly contact the stenosed region when the inflatable balloon is expanded; and the cylindrically shaped interposed member and the restenosis-restraining biologically active agent on the outer surface of the inflatable balloon being configured to contact one another when the treatment device is moved in the living body towards the stenosed region while the cylindrically shaped interposed member is positioned radially between the protective sleeve and the restenosis-restraining biologically active agent. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification