Device and method for modulating renal function
First Claim
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1. A device, comprising:
- a controller;
pulse generation circuitry operable by the controller;
one or more stimulation electrodes connected to the pulse generation circuitry adapted for endolymphatic disposition near the renal nerve; and
wherein the controller is programmed to operate the pulse generation circuitry to deliver neural stimulation to the renal nerve.
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Abstract
Renal function may be modulated by an implantable device having one or more leads or catheters disposed near the kidney via the lymphatic system. In one embodiment, lymphatic drainage from the kidney is modulated to increase or decrease tubular reabsorption of salt and water. The renal function modulation therapy may be delivered in an open-loop or closed-loop fashion, with the latter dependent upon a physiological variable such as blood pressure or cardiac output.
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Citations
20 Claims
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1. A device, comprising:
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a controller; pulse generation circuitry operable by the controller; one or more stimulation electrodes connected to the pulse generation circuitry adapted for endolymphatic disposition near the renal nerve; and wherein the controller is programmed to operate the pulse generation circuitry to deliver neural stimulation to the renal nerve. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method, comprising:
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introducing one or more stimulation electrodes into a renal lymphatic vessel near the renal nerve; connecting the stimulation electrodes to pulse generation circuitry operated by a controller; programming the controller to operate the pulse generation circuitry to deliver neural stimulation to the renal nerve. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification