Multi-field cancer therapy apparatus and method of use thereof

• US 9,616,252 B2
• Filed: 06/11/2014
• Issued: 04/11/2017
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Balakin
• Inventors: Balakin, Vladimir
• Primary Examiner(s): Smith, David E
• Application Number:
  US14/302,253
• Publication Number:
  US 20150360057A1
• Time in Patent Office: 1,035 Days
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1095 Elements inserted into the radiation path within the system, e.g. filters or wedges
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries

Abstract

A multi-field cancer therapy apparatus and method of use thereof is described increasing dimensionality of incident tumor treatment angles while minimizing distance between a final beamline focusing magnet and the patient. Increased dimensionality of incident tumor treatment angles is achieved through coordinated use of one or more of: a rotatable targeting magnet; a first patient rotation platform rotating the patient around, without intersecting, a vertical axis; a second patient rotation platform rotating a body part through a movable vertical axis; and patient tilt. The increased charged particle incident angle dimensionality distributes Bragg peak tail energy about the tumor. Dynamic energy and/or intensity control of the charged particle beam as a function of efficiency of beam delivery based on tumor shape further reduces Bragg peak tail energy delivered to healthy tissue about the tumor.

Claims

1. A method for positioning a tumor of a patient relative to positively charged particles, comprising the steps of:

accelerating the positively charged particles with an accelerator;

guiding the positively charged particles from said accelerator to the tumor using a beamline of guiding magnets, said beamline comprising a rotatable magnet;

supporting the patient on a first rotatable platform; and

co-rotating said first rotatable platform and said rotatable magnet.

2. The method of claim 1, further comprising the step of:

providing a penultimate magnet in said beamline; and

directing the positively charged particles from said penultimate magnet to said rotatable magnet along an axis greater than twenty-five degrees off of vertical.

3. The method of claim 2, further comprising the step of:

vertically scanning the charged particles in the tumor, said step of vertically scanning comprising the steps of;

varying at least one of current and voltage delivered to a coil proximate a gap in a core of said rotatable magnet;

said step of varying altering a magnetic field across the gap; and

passing the positively charged particles through the gap.

4. The method of claim 3, further comprising the step of:

scanning a vertical slice of the tumor, said step of scanning the vertical slice of the tumor comprising the steps of;

controlling energy of the positively charged particles by timing transmission of the positively charged particles through an extraction foil, said extraction foil positioned in a charged particle beam path prior to a Lambertson extraction magnet; and

repeating said step of varying and controlling.

5. The method of claim 1, further comprising the step of:

treating a vertical slice of the tumor using the positively charged particles, wherein the positively charged particles comprise C⁶⁺ particles.

6. The method of claim 5, said step of treating a vertical slice comprising the steps of:

controlling energy of the C⁶⁺ particles by timing transmission of the C⁶⁺ particles through an extraction foil;

varying a guiding magnetic field across a gap in said rotatable magnet; and

passing the C⁶⁺ particles through the gap.

7. The method of claim 1, further comprising the step of:

rotating the patient on a second rotatable platform, said second rotatable platform rotating about a fixed point of said first rotatable platform.

8. The method of claim 7, further comprising the steps of:

at a first point in time, delivering the positively charged particles from the rotatable magnet along a first downward line comprising a first horizontal vector; and

at a second point in time after said steps of;

(1) co-rotating said first rotatable platform and (2) rotating the patient on said second rotatable platform, delivering the charged particles from said rotatable magnet along a second downward line comprising a second horizontal vector, wherein the first horizontal vector and the second horizontal vector point in opposite directions.

9. The method of claim 1, further comprising the step of:

at a first point in time, delivering the positively charged particles from the rotatable magnet along a first downward line comprising a first horizontal vector; and

at a second point in time after said step of co-rotating, delivering the positively charged particles from said rotatable magnet along a second downward line comprising a second horizontal vector, the first horizontal vector and the second horizontal vector pointing in opposite directions.

10. The method of claim 7, further comprising the steps of:

passing the positively charged particles into the tumor through a ventral/dexter side of the tumor at the first point in time; and

passing the positively charged particles into the tumor through a ventral/sinister side of the tumor at the second point in time.

11. The method of claim 9, further comprising the steps of:

supporting the patient on a patient support, said patient support positioned by said first rotatable platform; and

tilting a longitudinal axis of said patient support relative to a horizontal axis.

12. The method of claim 11, said step of tilting further comprising the steps of:

orientating a first side between a ventral side and a dexter side of the patient toward the rotatable magnet at a first point in time; and

orientating a second side between the ventral side and a sinister side of the patient toward the rotatable magnet at a second point in time.

13. The method of claim 1, further comprising the steps of:

supporting the patient on a patient support, said patient support positioned by said first rotatable platform; and

tilting a longitudinal axis of said patient support relative to a horizontal axis, said step of tilting further comprising the steps of;

orientating a first side of the patient, between a ventral side and a dexter side of the patient, toward the rotatable magnet at a first point in time; and

orientating a second side of the patient, between the ventral side and a sinister side of the patient, toward the rotatable magnet at a second point in time.

14. The method of claim 12, further comprising the steps of:

supporting the patient on a patient support, said patient support supported by said first rotatable platform; and

maintaining a fixed distance between said rotatable magnet and a point of said patient support during said step of co-rotating said rotatable magnet and said first rotatable platform.

15. The method of claim 1, further comprising the step of:

supporting the patient on a patient support platform, said patient support platform supported by said first rotatable platform, said patient support platform vertically higher than an acceleration plane of said accelerator.

16. An apparatus for positioning a tumor of a patient relative to positively charged particles, comprising:

an accelerator;

a beamline comprising a rotatable magnet, said beamline configured to guide the positively charged particles from said accelerator to the tumor during use;

a first rotatable platform configured to position the patient during use; and

means for co-rotating said rotatable magnet and said first rotatable platform.

17. The apparatus of claim 16, further comprising:

an extraction foil; and

a controller, said controller timing transmission of the positively charged particles through said extraction foil to control energy of the positively charged particles.

18. The apparatus of claim 17, said rotatable magnet further comprising:

means for vertically scanning the positively charged particles, comprising;

a core comprising a gap therethrough;

a coil wound proximate the gap;

a power supply electrically linked to said coil; and

a controller configured to vary at least one of a current and a voltage from said power supply to said coil to scan a magnetic field across the gap, the magnetic field scanning the positively charged particles vertically.

19. The apparatus of claim 16, further comprising:

a patient support configured to support the patient, said patient support supported by said first rotatable platform; and

a fixed distance between said rotatable magnet and a point of said patient support, said fixed distance maintained with co-rotation of said rotatable magnet and said first rotatable platform.

20. The apparatus of claim 16, further comprising:

a patient support platform configured to support the patient, said patient support platform supported by said first rotatable platform, said patient support platform positioned vertically higher than an acceleration plane of said accelerator.