Device and methods for mobile monitoring and assessment of clinical function through sensors and interactive patient responses

• US 9,619,613 B2
• Filed: 10/19/2015
• Issued: 04/11/2017
• Est. Priority Date: 06/22/2012
• Status: Active Grant

• Current Assignee: Integrated Deficit Examinations, LLC
• Original Assignee: Integrated Deficit Examinations, LLC
• Inventors: Meyer, Brett C., Zivin, Justin A.
• Primary Examiner(s): Thomson, William
• Assistant Examiner(s): SANDS, DAVIN K
• Application Number:
  US14/887,162
• Publication Number:
  US 20160042123A1
• Time in Patent Office: 540 Days
• Field of Search: None
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 2560/0475 Special features of memory means, e.g. removable memory cards
• CPC Class Codes: A61B 2562/0204 Acoustic sensors
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/1121 Determining geometric values, e.g. centre of rotation or angular range of movement
• CPC Class Codes: A61B 5/16 Devices for psychotechnics using teaching or educational appliances G09B1/00 - G09B7/00; Testing reaction times ; Devices for evaluating the psychological state
• CPC Class Codes: A61B 5/224 Measuring muscular strength
• CPC Class Codes: A61B 5/225 of the fingers, e.g. by monitoring hand-grip force
• CPC Class Codes: A61B 5/4005 for evaluating the sensory system A61B5/12, A61B5/4058 take precedence
• CPC Class Codes: A61B 5/4076 Diagnosing or monitoring particular conditions of the nervous system A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/4082 Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette
• CPC Class Codes: A61B 5/4088 Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7271 Specific aspects of physiological measurement analysis A61B5/316, A61B5/349 and A61B5/374 take precedence
• CPC Class Codes: A61B 5/74 Details of notification to user or communication with user or patient indicating measured values G01D7/00; user input means input or output arrangements for computers G06F3/00
• CPC Class Codes: A61B 5/7405 using sound
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7455 characterised by tactile indication, e.g. vibration or electrical stimulation
• CPC Class Codes: G16H 30/40 for processing medical images, e.g. editing
• CPC Class Codes: G16H 40/67 : for remote operation
• CPC Class Codes: G16H 50/30 : for calculating health indices; for individual health risk assessment

Abstract

Methods and systems are disclosed for sensing and assessing a patients responses to tests using a device that may include tactile input, voice input, still image analysis, and responses to visual and auditory stimuli. In one example, a method includes obtaining interactive clinical assessment data using a remote client device and a computer-based control device, the method including providing on a display of a remote client device one or more test prompts for conducting an interactive clinical assessment, each displayed test prompt instructing a user to perform an action using the remote client device in response to the test prompt, and providing on the display of the remote client device one or more potential responses of actions that may be performed in response to the test prompt.

Claims

1. A method of obtaining interactive clinical assessment data using a remote client device, the method comprising:

providing by a handheld remote client device a plurality of test prompts for conducting an interactive clinical assessment, each test prompt instructing a patient to perform an action using the client device, the client device comprising a processor, a display, at least one handle mechanically integrated with the client device, a circuit configured to produce a vibration test prompt on the at least one handle, and a plurality of sensors integrated in the client device;

receiving information from the plurality of sensors indicative of a user input response to the test prompts, the information including

data indicative of movement of the client device,

image data capturing the position of the patient'"'"'s eyes,

image data capturing the pupils of eyes of the patient,

touch data indicative of the patient'"'"'s peripheral vision,

image data capturing the patient'"'"'s face,

grip pressure data,

touch data selecting a displayed target,

audio data or touch data responsive to the vibration test prompt,

audio data indicative of clarity of speech,

audio data or touch data input data representing identifying objects provided on the display, and

audio data or touch data indicative of the number of objects provided on the display; and

generating, by the processor, response information indicative of the information received from the plurality of sensors.

2. The method of claim 1, further comprising sending, by the client device, the generated response information over a communications network.

3. The method of claim 1, wherein the client device further comprises a pressure sensor disposed on the at least one handle of the client device for sensing hand grip pressure, a movement sensor for sensing horizontal and vertical motion of the client device, a microphone and voice recognition system for receiving an audio input, a camera positioned to generate an image of an area in front of the display, and a touchscreen for sensing a touch data input at the display.

4. The method of claim 2, wherein the data indicative of movement of the client device is received from the movement sensor, the image data is received from by the camera, the grip pressure data is received from the pressure sensor, the touch data is received from the touchscreen, and the audio data received from the microphone and voice recognition circuit.

5. The method of claim 1, wherein providing a plurality of test prompts comprises providing visual test prompts on a display of the client device.

6. The method of claim 1, wherein providing a plurality of test prompts comprises providing audio test prompts using a speaker of the client device.

7. The method of claim 1, further comprising receiving clinical tests at the remote device, and wherein the plurality of test prompts are based at least in part on the received clinical tests.

8. The method of claim 1, further comprising receiving clinical test parameters at the remote client device, and wherein the plurality of test prompts are based at least in part on the received test parameters.

9. The method of claim 1, further comprising receiving patient information at the remote client device, and wherein the plurality of test prompts are based at least in part on the received patient information.

10. The method of claim 1, further comprising:

receiving the response information sent by the remote client device at a control device,

evaluating at the control device the response information, and

determining the status of the patient based on evaluating the response information.

11. The method of claim 10, further comprising sending an alert signal from the control device based on a determined patient status.

12. The method of claim 1, further comprising sending clinical tests, test parameters, and patient information from a control device to the remote client device, wherein the plurality of test prompts and one or more potential responses of actions that may be performed in response to the plurality of test prompts are at least partly based on the based clinical tests, test parameters, or patient information.

13. The method of claim 1, further comprising evaluating the response information to determine a change from baseline results of a particular patient.

14. The method of claim 1, further comprising:

receiving a series of tests, a series of parameters and a patient profile for responses at the remote client device,

determining response information indicative of responses received at the remote client device;

transmitting the response information to the control device; and

evaluating the response information at the control device to determine a clinical status of the patient.

15. The method of claim 14, further comprising sending, by a client device, the response information over a communications network.

16. The method of claim 1, further comprising receiving EEG data at the client device while providing a test prompt for the patient to move the client device.

17. The method of claim 1, further comprising providing a test prompt for the patient to move eyes fully to the left or right while receiving image data capturing the position of the patient'"'"'s eyes.

18. The method of claim 1, further comprising providing a test prompt for the patient to grip the at least one handle of the client device while receiving the grip pressure data.

19. A method of obtaining interactive clinical assessment data using a remote client device, the method comprising:

providing by a handheld remote client device a plurality of test prompts for conducting an interactive clinical assessment, each test prompt instructing a patient to perform an action using the client device, the client device comprising a processor, a display, at least one handle mechanically integrated with the client device, a circuit configured to produce a vibration test prompt on the at least one handle, and a plurality of sensors integrated in the client device, plurality of sensors including at least one pressure sensor integrated with the at least one handle, a movement sensor, a voice recognition system, a touchscreen, a camera, and a touchscreen;

receiving information from the plurality of sensors indicative of a user input response to the test prompts, the information including at least one of;

data indicative of movement of the client device,

image data capturing the position of the patient'"'"'s eyes,

image data capturing the pupils of eyes of the patient,

touch data indicative of the patient'"'"'s peripheral vision,

image data capturing the patient'"'"'s face,

grip pressure data,

touch data selecting a displayed target,

audio data or touch data responsive to the vibration test prompt,

audio data indicative of clarity of speech,

audio data or touch data input data representing identifying objects provided on the display, and

audio data or touch data indicative of the number of objects provided on the display; and

generating, by the processor, response information indicative of the information received from the plurality of sensors.

20. The method of claim 19, further comprising sending, by the client device, the generated response information over a communications network to a control device for further processing.