Cerebral vasculature device

• US 9,622,770 B2
• Filed: 11/06/2014
• Issued: 04/18/2017
• Est. Priority Date: 09/22/2006
• Status: Active Grant

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Trapp, Benjamin M., Friedman, Nathan L., Vonesh, Michael J.
• Primary Examiner(s): LOUIS, RICHARD G
• Application Number:
  US14/535,253
• Publication Number:
  US 20150127035A1
• Time in Patent Office: 894 Days
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0071 spherical
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: D04C 1/06 Braid or lace serving particular purposes
• CPC Class Codes: D10B 2101/20 Metallic fibres
• CPC Class Codes: D10B 2509/06 Vascular grafts; stents

Abstract

Novel cerebral vasculature devices are disclosed, including thrombectomy removal devices that include a continuous braided structure, a proximal portion, a distal portion, and a first expandable portion located between the proximal portion and the distal portion. The braided structure includes a plurality of wires. The proximal portion and the distal portion include polymer imbedded at least partially into the braided structure. The device is useful for removing thrombus from a patient'"'"'s vasculature.

Claims

1. A cerebral vascular device for capture and removal of thrombus, said cerebral vascular device comprising:

a catheter defining a lumen extending longitudinally therethrough, the catheter having a continuous braided structure comprising a plurality of wires, the catheter having a proximal portion wherein a polymer is embedded substantially throughout the braided structure, the catheter having a distal portion, the catheter having first and second expandable portions disposed between the proximal portion and the distal portion and an intermediate portion located between the first expandable portion and the second expandable portion, the braided structure along the distal portion and first and second expandable portions of the catheter being exposed and not covered by the polymer,

an elongated core wire extending longitudinally through the lumen; and

an atraumatic component being attached to the core wire and being entirely distal of the braided structure;

wherein, in response to axial displacement of the proximal and distal portions of the braided structure toward each other, the first and second expandable portions expand radially outwardly to a maximum expanded diameter and flatten axially and the intermediate portion and remaining portions of the braided structure are restrained from axially expanding and remain aligned with the lumen of the catheter, and

wherein the braid angle of the first and second expandable portions is about less than or equal to 10 degrees as measured from a longitudinal axis of the braided structure, and the intermediate portion and portions of the braided structure adjacent the first and second expandable portions have a braid angle that is substantially greater than 10 degrees as measured from a longitudinal axis of the braided structure such that the intermediate portion and remaining portions of the braided structure are restrained from axially expanding and remain aligned with the lumen of the catheter.

2. The cerebral vascular device of claim 1, wherein the braid angle of the first expandable portion is about less than or equal to 8 degrees as measured from the longitudinal axis of the braided structure.

3. The device of claim 1, wherein the plurality of wires comprise metal wires.

4. The device of claim 3, wherein the wires of the braided structure have an outer diameter of about 0.020 inch or less.

5. The device of claim 4, wherein the wires of the braided structure have an outer diameter of about 0.017 inch or less.

6. The device of claim 5, wherein the plurality of wires comprise nitinol.

7. The device of claim 4, wherein the wires have a round profile.

8. The device of claim 1, wherein the polymer comprises a material selected from the group consisting of polyimide, peba, polyurethane, nylon, silicone, and polyethylene.

9. The cerebral vascular device of claim 1, wherein the braid angle of the second expandable portion is about less than or equal to 8 degrees as measured from the longitudinal axis of the braided structure.

10. The device of claim 1, wherein the intermediate portion comprises polymer imbedded at least partially into the braided structure.

11. The device of claim 1, wherein the intermediate portion is radially constrained by a polymer covering.

12. The device of claim 1, wherein the intermediate portion is radially constrained by a metal band.

13. The device of claim 1, wherein the atraumatic component has an outer diameter at least equal to the inner diameter of the braided structure distal portion.

14. The cerebral vascular device of claim 13, wherein the atraumatic component is selected from the group consisting of polymer tubular structures and metal coils.

15. The cerebral vascular device of claim 14, wherein the metal coil comprises radioopaque material.

16. The cerebral vascular device of claim 14, wherein the radiopaque material comprises a material selected from the group consisting of platinum, gold, iridium, and platinum/iridium alloy.

17. A cerebral vascular device for capture and removal of thrombus, the cerebral vascular device comprising:

a catheter defining a lumen extending longitudinally therethrough, the catheter having a continuous braided structure comprising a plurality of wires, the catheter having a proximal portion wherein a polymer is embedded substantially throughout the braided structure, the catheter having a distal portion, the catheter having first and second expandable portions disposed between the proximal portion and the distal portion and an intermediate portion disposed between the first and second expandable portions, the braided structure along the distal portion and first and second expandable portions of the catheter being exposed and not covered by the polymer;

an elongated core wire extending longitudinally through the lumen; and

an atraumatic component being attached to the core wire and being entirely distal of the braided structure;

wherein, in response to axial displacement of the proximal and distal portions of the braided structure toward each other, the first and second expandable portions expand radially outwardly to a maximum expanded diameter and flatten axially and the intermediate portion and remaining portions of the braided structure are substantially prevented from axially expanding and remain aligned with the lumen of the catheter, wherein the braid angle of the intermediate portion is configured to restrained the intermediate portion from axially expanding and to remain aligned with the lumen of the catheter.