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Method for retrovirus removal

  • US 9,623,352 B2
  • Filed: 07/29/2011
  • Issued: 04/18/2017
  • Est. Priority Date: 08/10/2010
  • Status: Active Grant
First Claim
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1. A method of removing retroviruses from a liquid sample comprising the steps of:

  • a) providing a liquid sample containing retroviruses,b) providing a filtration medium comprising a porous nanofiber mat made by electrospinning a polymer, wherein the porous nanofiber mat has a retrovirus Log Reduction Value (LRV) greater than about 6, a porosity from about 80% to about 95%, and a liquid permeability greater than about 100 LMH/psi, and wherein the nanofiber mat has a fiber diameter effective for retention of retroviruses by size-based exclusion, andc) passing the liquid sample containing the retroviruses through the filtration medium such that the retroviruses are retained by the filtration medium.

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